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Anti-B7-H3 Antibody (7G651) 是一种 Rabbit 抗体,靶向 B7-H3。Anti-B7-H3 Antibody (7G651) 可用于 ELISA。
Anti-B7-H3 Antibody (7G651) 是一种 Rabbit 抗体,靶向 B7-H3。Anti-B7-H3 Antibody (7G651) 可用于 ELISA。
产品描述 | Anti-B7-H3 Antibody (7G651) is a Rabbit antibody targeting B7-H3. Anti-B7-H3 Antibody (7G651) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 7G651 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse B7-H3/CD276 (rM B7-H3/CD276; TMPY-04064; NP_598744.1; Met1-Phe244). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally related to the B7 family of ligands by the presence of a single set of immunoglobulin-V-like and immunoglobulin-C-like (VC) domains. Previous studies have correlated its overexpression with poor prognosis and decreased tumor-infiltrating lymphocytes in various carcinomas including uterine endometrioid carcinomas, and mounting evidence supports an immuno-inhibitory role in ovarian cancer prognosis. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse B7-H3/CD276 Protein (TMPY-04064) |
抗原种属 | Mouse |
研究领域 | Cancer Drug Targets |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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