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Anti-B7-H3 Antibody (7G651)

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产品编号 TMAY-03503

Anti-B7-H3 Antibody (7G651) 是一种 Rabbit 抗体,靶向 B7-H3。Anti-B7-H3 Antibody (7G651) 可用于 ELISA。

Anti-B7-H3 Antibody (7G651)

Anti-B7-H3 Antibody (7G651)

Rating icon 还可以
产品编号 TMAY-03503

Anti-B7-H3 Antibody (7G651) 是一种 Rabbit 抗体,靶向 B7-H3。Anti-B7-H3 Antibody (7G651) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-B7-H3 Antibody (7G651) is a Rabbit antibody targeting B7-H3. Anti-B7-H3 Antibody (7G651) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
7G651
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse B7-H3/CD276 (rM B7-H3/CD276; TMPY-04064; NP_598744.1; Met1-Phe244).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally related to the B7 family of ligands by the presence of a single set of immunoglobulin-V-like and immunoglobulin-C-like (VC) domains. Previous studies have correlated its overexpression with poor prognosis and decreased tumor-infiltrating lymphocytes in various carcinomas including uterine endometrioid carcinomas, and mounting evidence supports an immuno-inhibitory role in ovarian cancer prognosis. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse B7-H3/CD276 Protein (TMPY-04064)
抗原种属
Mouse
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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