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Anti-P2RX7 Polyclonal Antibody

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货号 TMAB-01314

别名 Purinergic receptor, P2Z receptor, P2X7, P2X purinoceptor 7, P2RX7, ATP receptor

Anti-P2RX7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 P2RX7。Anti-P2RX7 Polyclonal Antibody 可用于 WB。

Anti-P2RX7 Polyclonal Antibody

Anti-P2RX7 Polyclonal Antibody

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货号 TMAB-01314 别名 Purinergic receptor, P2Z receptor, P2X7, P2X purinoceptor 7, P2RX7, ATP receptor

Anti-P2RX7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 P2RX7。Anti-P2RX7 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-P2RX7 Polyclonal Antibody is a Rabbit antibody targeting P2RX7. Anti-P2RX7 Polyclonal Antibody can be used in WB.
别名Purinergic receptor, P2Z receptor, P2X7, P2X purinoceptor 7, P2RX7, ATP receptor
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
验证活性
Sample:
Lane 1: Human U937 cell lysates
Lane 2: Human U251 cell lysates
Lane 3: Human SH-SY5Y cell lysates
Primary: Anti-P2RX7 (TMAB-01314) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 69 kDa
Observed band size: 74 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.
抗原信息
免疫原
KLH conjugated synthetic peptide: human P2RX7
抗原种属
Human
基因名称
P2RX7
基因ID
5027
蛋白名称
P2X purinoceptor 7
Uniprot ID
Q99572
研究领域
P2X Receptors
功能
The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
化学信息
分子量Theoretical: 69 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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