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SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated

SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated

产品编号 TMPK-00996
别名: BSRPC, BSRP-C, SEZ6, SEZ-6

Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface. SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 100.7 kDa and the accession number is Q53EL9-1.

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SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated
规格 价格/CNY 货期 数量
100 μg ¥ 5,180 5日内发货
500 μg ¥ 20,700 5日内发货
1 mg ¥ 34,600 5日内发货
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产品目录号及名称: SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated (TMPK-00996)
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生物活性
技术参数
产品性质
参考文献
生物活性 Immobilized Biotinylated Human SEZ6, His Tag at 2μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 10.0ng/ml determined by ELISA.
产品描述 Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface. SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 100.7 kDa and the accession number is Q53EL9-1.
种属 Human
表达系统 HEK293 Cells
标签 C-His-Avi
蛋白编号 Q53EL9-1
别名 BSRPC, BSRP-C, SEZ6, SEZ-6
蛋白构建 Leu20-His925
蛋白纯度 > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量 100.7 kDa (predicted). Due to glycosylation, the protein migrates to 170-200 kDa based on Tris-Bis PAGE result.
内毒素 < 1 EU/μg by the LAL method.
缓冲液 Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
存储

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.

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Keywords

SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated SEZ 6 BSRPC BSRP-C SEZ6 SEZ-6 recombinant recombinant-proteins proteins protein

 

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