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顶部生物活性储存和溶解信息计算器

Anti-RIPK1 Antibody (1B304)

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Anti-RIPK1 Antibody (1B304)
产品编号 TMAC-03610
别名 RIPK1, RIP1, RIP, Receptor-interacting serine/threonine-protein kinase 1, Receptor-interacting protein 1 (RIP-1), Cell death protein RIP

Anti-RIPK1 Antibody (1B304) 是一种 Rabbit 抗体，靶向 RIPK1。Anti-RIPK1 Antibody (1B304) 可用于 WB,FCM。

Anti-RIPK1 Antibody (1B304)

Anti-RIPK1 Antibody (1B304)

Rating icon 还可以
Anti-RIPK1 Antibody (1B304)
产品编号 TMAC-03610 别名 RIPK1, RIP1, RIP, Receptor-interacting serine/threonine-protein kinase 1, Receptor-interacting protein 1 (RIP-1), Cell death protein RIP

Anti-RIPK1 Antibody (1B304) 是一种 Rabbit 抗体，靶向 RIPK1。Anti-RIPK1 Antibody (1B304) 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-RIPK1 Antibody (1B304) is a Rabbit antibody targeting RIPK1. Anti-RIPK1 Antibody (1B304) can be used in WB,FCM.
别名RIPK1, RIP1, RIP, Receptor-interacting serine/threonine-protein kinase 1, Receptor-interacting protein 1 (RIP-1), Cell death protein RIP
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of RIP on Hela cells lysates using anti-RIP antibody at 1/1,000 dilution.
2. Flow cytometric analysis of 293 cells with RIP antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
WB
FCM
推荐剂量
WB: 1:1000-5000; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景In contrast to growth factors which promote cell proliferation, FAS ligand (FAS-L) and the tumor necrosis factors (TNFs) rapidly induce apoptosis. Cellular response to FAS-L and TNF is mediated by structurally related receptors containing a conserved "death domain" and belonging to the TNF receptor superfamily. TRADD, FADD and RIP are FAS/TNF-R1 interacting proteins that contain a death domain homologous region (DDH). TRADD (TNF-R1-associated death domain) and FADD (FAS-associated death domain) associate with the death domains of both FAS and TNF-R1 via their DDH regions. Overexpression of TRADD leads to NFkB activation and apoptosis in the absence of TNF. Overexpression of FADD causes apoptosis, which can be blocked by the cow pox protein CrmA, suggesting that FADD lies upstream of ICE and possibly other serine proteases. The receptor interacting protein, RIP, associates with FAS exclusively via its DDH and this association is abrogated in lpr mutants. Unlike TRADD and FADD, RIP contains a putative amino terminal kinase domain.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q13546
化学信息
分子量Theoretical: 76 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

RIPK 1RIP-1RIP 1

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4个月前
5.0
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