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别名 匹地利珠单抗, MDV9300, CT-011
Pidilizumab (CT-011) 是一种人源化单克隆抗体,其通过靶向 PD-1 受体和 Notch 配体 DLL1 来调节抗肿瘤免疫反应。该抗体能够增强 T 细胞和自然杀伤 (NK) 细胞的活性,在血液系统恶性肿瘤,特别是滤泡性淋巴瘤的研究中展现出良好的临床潜力。
Pidilizumab (CT-011) 是一种人源化单克隆抗体,其通过靶向 PD-1 受体和 Notch 配体 DLL1 来调节抗肿瘤免疫反应。该抗体能够增强 T 细胞和自然杀伤 (NK) 细胞的活性,在血液系统恶性肿瘤,特别是滤泡性淋巴瘤的研究中展现出良好的临床潜力。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | 待询 | 待询 | |
| 5 mg | 待询 | 待询 |
| 产品描述 | Pidilizumab (CT-011) is a humanized monoclonal antibody that modulates anti-tumor immune responses by targeting the PD-1 receptor and the Notch ligand DLL1. It enhances the activity of T cells and natural killer (NK) cells, demonstrating significant clinical potential in the study of hematologic malignancies, particularly follicular lymphoma. |
| 别名 | 匹地利珠单抗, MDV9300, CT-011 |
| 反应种属 | Human |
| 应用 | ELISA FACS Functional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 同型 | IgG1 |
| 偶联 | Unconjugated |
| Uniprot ID | |
| 靶点 | PD-1 |
| CAS No. | 1036730-42-3 |
| 存储 | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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