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Anti-CD186 Monoclonal Antibody (6P381) 是一种 Mouse 抗体,靶向 CD186。Anti-CD186 Monoclonal Antibody (6P381) 可用于 WB,FCM。
别名 TYMSTR, STRL33, CXCR6, CDw186, BONZO
Anti-CD186 Monoclonal Antibody (6P381) 是一种 Mouse 抗体,靶向 CD186。Anti-CD186 Monoclonal Antibody (6P381) 可用于 WB,FCM。

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| 产品描述 | Anti-CD186 Monoclonal Antibody (6P381) is a Mouse antibody targeting CD186. Anti-CD186 Monoclonal Antibody (6P381) can be used in WB,FCM. |
| 别名 | TYMSTR, STRL33, CXCR6, CDw186, BONZO |
| Ig Type | IgG1 |
| 克隆号 | 6P381 |
| 反应种属 | Human |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human CD186 expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | CXCR6 |
| 基因ID | |
| 蛋白名称 | C-X-C chemokine receptor type 6 |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |