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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CDH1 Antibody (1P971)

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货号 TMAH-00245

别名 UVO, LCAM, E-Cadherin, E-cad, ECAD, CDHE, CDH1, CD324, cadherin 1, type 1, E-cadherin (epithelial), Arc-1

Anti-CDH1 Antibody (1P971) 是一种抗体，靶向 CDH1。Anti-CDH1 Antibody (1P971) 可用于 ELISA,IHC。

Anti-CDH1 Antibody (1P971)

Anti-CDH1 Antibody (1P971)

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货号 TMAH-00245 别名 UVO, LCAM, E-Cadherin, E-cad, ECAD, CDHE, CDH1, CD324, cadherin 1, type 1, E-cadherin (epithelial), Arc-1

Anti-CDH1 Antibody (1P971) 是一种抗体，靶向 CDH1。Anti-CDH1 Antibody (1P971) 可用于 ELISA,IHC。

规格价格库存数量
50 μL
¥ 1,310
5日内发货
100 μL
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-CDH1 Antibody (1P971) is an antibody targeting CDH1. Anti-CDH1 Antibody (1P971) can be used in ELISA,IHC.
别名UVO, LCAM, E-Cadherin, E-cad, ECAD, CDHE, CDH1, CD324, cadherin 1, type 1, E-cadherin (epithelial), Arc-1
Ig Type
Rabbit IgG
克隆号
1P971
反应种属
Human
验证活性
IHC image of TMAH-00245 diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
应用ELISAIHC
推荐剂量
IHC:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Cell junction, adherens junction. Cell membrane; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Note=Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane.
组织特异性Non-neural epithelial tissues.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. (Microbial infection) Serves as a receptor for Listeria monocytogenes; internalin A (InlA) binds to this protein and promotes uptake of the bacteria.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human E Cadherin
抗原种属
Human
基因名称
CDH1
基因ID
999
Uniprot ID
P12830
研究领域
Cancer, Developmental biology, Signal transduction
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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关键词

epithelialCDH-1CDH 1CD-324CD 324cadherin 1, type 1, E-cadherin
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