C-MPL Protein, Rat, Recombinant (hFc)

C-MPL Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 80.7 kDa and the accession number is A0A1W2Q6N1.

规格	价格/CNY		数量
50 μg	￥ 2,260	现货
100 μg	￥ 3,880	5日内发货
200 μg	￥ 6,630	5日内发货
500 μg	￥ 13,410	5日内发货

规格

价格/CNY

货期

数量

50 μg

￥ 2,260

现货

100 μg

￥ 3,880

5日内发货

200 μg

￥ 6,630

5日内发货

500 μg

￥ 13,410

5日内发货

生物活性	Testing in progress
产品描述	C-MPL Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 80.7 kDa and the accession number is A0A1W2Q6N1.

种属	Rat
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	A0A1W2Q6N1
别名	MPL proto-oncogene, thrombopoietin receptor, MPL
蛋白构建	The Rat MPL (XP_001072502.1) (Met1-Ala500) was expressed with the Fc region of Human IgG1 at the C-terminus.
蛋白纯度	> 95 % as determined by SDS-PAGE.
分子量	80.7 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number of cells of hematopoietic origin. C-MPL is homologous with members of the hematopoietic receptor superfamily. The presence of anti-sense oligodeoxynucleotides of C-Mpl inhibited megakaryocyte colony formation. Thrombopoietin is the ligand for C-Mpl. It was shown to be the major regulator of megakaryocytopoiesis and platelet formation. Defects in c-MPL are a cause of congenital amegakaryocytic thrombocytopenia which is a disease characterized by isolated thrombocytopenia and Megakaryocytopenia with no physical anomalies. Defects in c-MPL also cause thrombocythemia type 2 and myelofibrosis with myeloid metaplasia.