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Anti-LILRB1/CD85j/ILT2 Antibody (5D841)
还可以产品编号 TMAY-02808
Anti-LILRB1/CD85j/ILT2 Antibody (5D841) 是一种 Mouse 抗体，靶向 LILRB1/CD85j/ILT2。Anti-LILRB1/CD85j/ILT2 Antibody (5D841) 可用于 FCM。
Anti-LILRB1/CD85j/ILT2 Antibody (5D841)
Anti-LILRB1/CD85j/ILT2 Antibody (5D841)
还可以产品编号 TMAY-02808
Anti-LILRB1/CD85j/ILT2 Antibody (5D841) 是一种 Mouse 抗体，靶向 LILRB1/CD85j/ILT2。Anti-LILRB1/CD85j/ILT2 Antibody (5D841) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-LILRB1/CD85j/ILT2 Antibody (5D841) is a Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody (5D841) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 5D841 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human LILRB1(CD85j) expression on human whole blood monocytes. Cells were stained with purified anti-Human LILRB1(CD85j), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD85 / ILT2 / ILR1 / LILRB1 (rh CD85 / ILT2 / ILR1 / LILRB1; TMPY-03995; ADJ55949.1; Met1-His458). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE). LILRB1 binds to a wide range of Major Histocompatibility Complex Class I molecules (MHCIs) and transduces negative signals that can, for example, prevent the killing of MHCI-expressing cells. LILRB1 transcription is correlated with surface protein expression on NK cells. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | PE |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human CD85 / ILT2 / ILR1 / LILRB1 Protein (TMPY-03995) |
| 抗原种属 | Human |
| 研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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