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Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody

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Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody
产品编号 TMAB-00014

Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody 是一种 Rabbit 抗体,靶向 8-Hydroxy-2'-deoxyguanosine。Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody

Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody

Rating icon 还可以
Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody
产品编号 TMAB-00014

Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody 是一种 Rabbit 抗体,靶向 8-Hydroxy-2'-deoxyguanosine。Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody is a Rabbit antibody targeting 8-Hydroxy-2'-deoxyguanosine. Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Rat,Species independent
验证活性
Tissue/cell: rat brain tissue (left panel was injury,Right panel was normal); 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-8-OHdG Polyclonal Antibody, Unconjugated (TMAB-00014) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
应用
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.
抗原信息
免疫原
KLH conjugated 8-OHdG
研究领域
Oxidative Stress,DNA / Nucleotides,Oxidative stress
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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