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Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody 是一种 Rabbit 抗体,靶向 8-Hydroxy-2'-deoxyguanosine。Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody 是一种 Rabbit 抗体,靶向 8-Hydroxy-2'-deoxyguanosine。Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,165 | 5日内发货 | |
100 μL | ¥ 1,960 | 5日内发货 | |
200 μL | ¥ 2,785 | 5日内发货 |
产品描述 | Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody is a Rabbit antibody targeting 8-Hydroxy-2'-deoxyguanosine. Anti-8-Hydroxy-2'-deoxyguanosine Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
Ig Type | IgG |
交叉反应 | Rat,Species independent |
验证活性 | Tissue/cell: rat brain tissue (left panel was injury,Right panel was normal); 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-8-OHdG Polyclonal Antibody, Unconjugated (TMAB-00014) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. |
应用 | |
推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease. |
免疫原 | KLH conjugated 8-OHdG |
研究领域 | Oxidative Stress,DNA / Nucleotides,Oxidative stress |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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