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Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. . IL-4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is P05112.

| 规格 | 价格 | 库存 | 数量 | 
|---|---|---|---|
| 5 μg | ¥ 358  | 6-8日内发货 | |
| 10 μg | ¥ 573  | 6-8日内发货 | |
| 20 μg | ¥ 938  | 5日内发货 | |
| 50 μg | ¥ 1,830  | 5日内发货 | |
| 100 μg | ¥ 3,100  | 5日内发货 | |
| 200 μg | ¥ 5,620  | 5日内发货 | |
| 500 μg | ¥ 12,400  | 5日内发货 | 
| 生物活性 | 1. Immobilized Human IL-4 at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Human IL-4 R alpha, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA (QC Test). 
2. Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is <0.2 ng/mL.  | 
| 产品描述 | Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. . IL-4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is P05112.  | 
| 种属 | Human  | 
| 表达系统 | HEK293 Cells  | 
| 标签 | C-His-Avi | 
| 蛋白编号 | P05112 | 
| 别名 | 白细胞介素,白介素,pitrakinra,MGC79402,interleukin 4,IL-4,IL4,BSF-1,BSF1,binetrakin,BCGF-1,BCGF1,BCDF,B cell growth factor 1  | 
| 蛋白构建 | His25-Ser153  | 
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE  | 
| 分子量 | 17.8 kDa (predicted). Due to glycosylation, the protein migrates to 23-25 kDa based on Tris-Bis PAGE result. | 
| 内毒素 | < 1 EU/μg by the LAL method. | 
| 蛋白性状 | Lyophilized powder | 
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. | 
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.  | 
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.  | 
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. | 
| 研究背景 | Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. .  |