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IL-4 Protein, Human, Recombinant (His & Avi)
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货号 TMPK-00034
别名 白细胞介素, 白介素, pitrakinra, MGC79402, interleukin 4, IL-4, IL4, BSF-1, BSF1, binetrakin, BCGF-1, BCGF1, BCDF, B cell growth factor 1
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. . IL-4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is P05112.
其他形式的 “IL-4 Protein, Human, Recombinant (His & Avi)”:
IL-4 Protein, Human, Recombinant (His & Avi)
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货号 TMPK-00034 别名 白细胞介素, 白介素, pitrakinra, MGC79402, interleukin 4, IL-4, IL4, BSF-1, BSF1, binetrakin, BCGF-1, BCGF1, BCDF, B cell growth factor 1
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. . IL-4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is P05112.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 358 | 现货 | |
| 10 μg | ¥ 573 | 现货 | |
| 20 μg | ¥ 938 | 3日内发货 | |
| 50 μg | ¥ 1,830 | 3日内发货 | |
| 100 μg | ¥ 3,100 | 现货 | |
| 200 μg | ¥ 5,620 | 5日内发货 | |
| 500 μg | ¥ 12,400 | 5日内发货 |
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产品介绍
生物活性
化学信息
储存&溶解度
| 产品描述 | Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. . IL-4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is P05112. |
| 生物活性 | 1. Immobilized Human IL-4 at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Human IL-4 R alpha, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA (QC Test).
2. Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is <0.2 ng/mL. |
| 研究背景 | Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. . |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-His-Avi |
| 蛋白编号 | P05112 |
| 蛋白构建 | His25-Ser153 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | 白细胞介素, 白介素, pitrakinra, MGC79402, interleukin 4, IL-4, IL4, BSF-1, BSF1, binetrakin, BCGF-1, BCGF1, BCDF, B cell growth factor 1 |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 分子量 | 17.8 kDa (predicted). Due to glycosylation, the protein migrates to 23-25 kDa based on Tris-Bis PAGE result. |
| 颜色 | White |
| 物理性状 | Lyophilized powder |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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