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Anti-GFAP Antibody (8M733) 是一种 Rabbit 抗体,靶向 GFAP。Anti-GFAP Antibody (8M733) 可用于 WB。
Anti-GFAP Antibody (8M733) 是一种 Rabbit 抗体,靶向 GFAP。Anti-GFAP Antibody (8M733) 可用于 WB。
产品描述 | Anti-GFAP Antibody (8M733) is a Rabbit antibody targeting GFAP. Anti-GFAP Antibody (8M733) can be used in WB. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8M733 |
交叉反应 | Human |
验证活性 | Anti-GFAP rabbit monoclonal antibody at 1:500 dilution. -Lane A: Mouse brain tissue lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:50 kDa. -Observed band size:45 kDa |
应用 | WB |
推荐剂量 | WB: 1:500-1:1000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the human GFAP. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | GFAP is a cell-specific marker which belongs to the intermediate filament family. It can distinguish astrocytes from other glial cells during development. GFAP is expressed in cells lacking fibronectin. It is a type III intermediate filaments protein which contains three domains: the head, rod and tail domains. GFAP functions in many important entral nervous system (CNS) processes, including cell communication and the functioning of the blood brain barrier. Improper GFAP regulation can cause multiple disorders. Defects in GFAP is related to Alexander disease which is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide corresponding to the center region of the human GFAP |
抗原种属 | Human |
研究领域 | Neuroinflammation |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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