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Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody

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Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody
产品编号 TMAC-00292
别名 p-Alpha-Synuclein (Y133), p-Alpha-Synuclein (Tyr133), Alpha-Synuclein (p-Y133), Alpha-Synuclein (p-Tyr133)

Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Alpha-Synuclein (Tyr133)。Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody 可用于 WB,IF。

Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody

Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody
产品编号 TMAC-00292 别名 p-Alpha-Synuclein (Y133), p-Alpha-Synuclein (Tyr133), Alpha-Synuclein (p-Y133), Alpha-Synuclein (p-Tyr133)

Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Alpha-Synuclein (Tyr133)。Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody 可用于 WB,IF。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,230
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Alpha-Synuclein (Tyr133). Anti-Phospho-Alpha-Synuclein (Tyr133) Polyclonal Antibody can be used in WB,IF.
别名p-Alpha-Synuclein (Y133), p-Alpha-Synuclein (Tyr133), Alpha-Synuclein (p-Y133), Alpha-Synuclein (p-Tyr133)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from C2C12 cells untreated or treated with Anisomycin using a-Synuclein (Phospho-Tyr133) Antibody TMAC-00292.
2. Immunofluorescence staining of methanol-fixed Hela cells using a-Synuclein (Phospho-Tyr133) Antibody TMAC-00292.
应用
WB
IF
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景SncA is a member of the synuclein family of structurally related proteins that are prominently expressed in the central nervous system, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and SncA and Snc-Beta inhibit phospholipase D2 selectively. SncA may serve to integrate presynaptic signaling and membrane trafficking. Aggregated SncA proteins form brain lesions that are hallmarks of neurodegenerative synucleinopathies. Defects in SncA play a role in the pathogenesis of Parkinson disease. SncA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer disease. SncA shares 95% sequence homology with rat SncA. Rat SncA is specifically expressed in brain and is associated with synaptosomal membranes in neurons
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of tyrosine 133 (E-G-Y(p)-Q-D) derived from Human a-Synuclein
抗原种属
human
Uniprot ID
P37840
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pAlpha-Synuclein (Y133)pAlpha-Synuclein (Tyr133)Alpha-Synuclein (pY133)Alpha-Synuclein (pTyr133)Alpha-Synuclein (phospho-Y133)Alpha-Synuclein (phospho-Tyr133)

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