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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CD45 Antibody (2U930)

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货号 TMAB-04002

Anti-CD45 Antibody (2U930) 是一种 Mouse 抗体，靶向 CD45。Anti-CD45 Antibody (2U930) 可用于 WB,FCM。

Anti-CD45 Antibody (2U930)

Anti-CD45 Antibody (2U930)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04002

Anti-CD45 Antibody (2U930) 是一种 Mouse 抗体，靶向 CD45。Anti-CD45 Antibody (2U930) 可用于 WB,FCM。

规格价格库存数量
200 μg
¥ 5,585
5日内发货
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD45 Antibody (2U930) is a Mouse antibody targeting CD45. Anti-CD45 Antibody (2U930) can be used in WB,FCM.
Ig Type
IgG1
克隆号
2U930
反应种属
Human
应用WBFCM
推荐剂量
WB: 1:500-1000; FCM: 0.5μg/Test
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Membrane; Single-pass type I membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling
抗原信息
免疫原
Recombinant Protein: human CD45
抗原种属
Human
基因名称
PTPRC
基因ID
5788
蛋白名称
Receptor-type tyrosine-protein phosphatase C
Uniprot ID
P08575
功能
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
化学信息
分子量Theoretical: 143 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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