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GOLPH2/GOLM1 Protein, Human, Recombinant (His)

Synonyms: PSEC0257, HEL46, GP73, GOLPH2, golgi membrane protein 1, C9orf155, bA379P1.3
货号 TMPY-02193 一键复制产品信息
Rating icon 很棒
SPR兼容缓冲液
26年秋季促销
26年新产品线折扣促销活动

Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2, and GOLM1, is a protein that belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in the colon, prostate, trachea, and stomach. It is expressed at a lower level in testis, muscle, lymphoid tissues, white blood cells, and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at a low level in the normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), GOLM1 is strongly expressed in hepatocyte-derived syncytial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes.

GOLPH2/GOLM1 Protein, Human, Recombinant (His)

一键复制产品信息
Rating icon 很棒
SPR兼容缓冲液
26年秋季促销
26年新产品线折扣促销活动
货号 TMPY-02193

别名 PSEC0257, HEL46, GP73, GOLPH2, golgi membrane protein 1, C9orf155, bA379P1.3

Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2, and GOLM1, is a protein that belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in the colon, prostate, trachea, and stomach. It is expressed at a lower level in testis, muscle, lymphoid tissues, white blood cells, and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at a low level in the normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), GOLM1 is strongly expressed in hepatocyte-derived syncytial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes.

GOLPH2/GOLM1 Protein, Human, Recombinant (His)
规格价格库存数量
5 μg
¥ 636
现货
10 μg
¥ 993
现货
20 μg
¥ 1,590
现货
50 μg
¥ 2,980
现货
100 μg
¥ 4,750
5日内发货
库存状态实时更新,以官网显示为准,现货产品可直接加购物车下单
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选择批次:
纯度: > 90 % as determined by SDS-PAGE
颜色: 白色
性状: Lyophilized powder
资源下载: COA重组蛋白用户指南

产品介绍


生物活性
产品描述
Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2, and GOLM1, is a protein that belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in the colon, prostate, trachea, and stomach. It is expressed at a lower level in testis, muscle, lymphoid tissues, white blood cells, and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at a low level in the normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), GOLM1 is strongly expressed in hepatocyte-derived syncytial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes.
生物活性
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2, and GOLM1, is a protein that belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in the colon, prostate, trachea, and stomach. It is expressed at a lower level in testis, muscle, lymphoid tissues, white blood cells, and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at a low level in the normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), GOLM1 is strongly expressed in hepatocyte-derived syncytial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes.
种属
Human
表达系统
HEK293 Cells
标签
C-His
蛋白编号Q8NBJ4-1
蛋白构建
A DNA sequence encoding the human GOLM1 isoform 1 (Q8NBJ4-1) (Val 40-Leu 401) was fused with a polyhistidine tag at the C-terminus and a Met at the N-terminus. Predicted N terminal: Met
蛋白纯度
> 90 % as determined by SDS-PAGE
蛋白性状
Lyophilized powder
缓冲液
Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法
Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
别名
PSEC0257, HEL46, GP73, GOLPH2, golgi membrane protein 1, C9orf155, bA379P1.3
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量42.7 kDa (predicted); 60 kDa (reducing conditions)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

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  • 重组蛋白稀释 计算器
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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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