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Anti-IL-1 alpha/IL1A Antibody (7K273)
还可以产品编号 TMAY-00314
Anti-IL-1 alpha/IL1A Antibody (7K273) 是一种 Mouse 抗体，靶向 IL-1 alpha/IL1A。Anti-IL-1 alpha/IL1A Antibody (7K273) 可用于 ELISA。
Anti-IL-1 alpha/IL1A Antibody (7K273)
Anti-IL-1 alpha/IL1A Antibody (7K273)
还可以产品编号 TMAY-00314
Anti-IL-1 alpha/IL1A Antibody (7K273) 是一种 Mouse 抗体，靶向 IL-1 alpha/IL1A。Anti-IL-1 alpha/IL1A Antibody (7K273) 可用于 ELISA。
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抗原信息
| 产品描述 | Anti-IL-1 alpha/IL1A Antibody (7K273) is a Mouse antibody targeting IL-1 alpha/IL1A. Anti-IL-1 alpha/IL1A Antibody (7K273) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7K273 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-1 alpha/IL1A (rh IL-1 alpha/IL1A; TMPY-00854; NP_000566.3; Ser113-Ala271). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. Cytokines can be classified into two groups: pro- and anti-inflammatory. Pro-inflammatory cytokines, including IFNgamma, IL-1, IL-6, and TNF-alpha, are predominantly derived from the innate immune cells and Th1 cells. Anti-inflammatory cytokines, including IL-10, IL-4, IL-13, and IL-5, are synthesized from Th2 immune cells. IL-1 alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. It is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IL-1 alpha/IL1A Protein (TMPY-00854) |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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