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TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant

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货号 TMPS-00158

别名 ZTNFR9, Tumor necrosis factor receptor superfamily member 10B, TRICKB, TRICK2B, TRICK2A, TRICK2, TRAIL-R2, TRAILR2, TRAIL receptor 2, TNFRSF10B, TNF-related apoptosis-inducing ligand receptor 2, KILLER/DR5, KILLER, DR5, Death receptor 5, CD262

TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant is expressed in E. coli. The accession number is O14763.

TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant
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TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant

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货号 TMPS-00158 别名 ZTNFR9, Tumor necrosis factor receptor superfamily member 10B, TRICKB, TRICK2B, TRICK2A, TRICK2, TRAIL-R2, TRAILR2, TRAIL receptor 2, TNFRSF10B, TNF-related apoptosis-inducing ligand receptor 2, KILLER/DR5, KILLER, DR5, Death receptor 5, CD262

TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant is expressed in E. coli. The accession number is O14763.

规格价格库存数量
5 μg
¥ 576
6-8日内发货
10 μg
¥ 945
6-8日内发货
20 μg
¥ 1,370
5日内发货
50 μg
¥ 2,260
5日内发货
100 μg
¥ 3,520
5日内发货
200 μg
¥ 5,480
5日内发货
500 μg
¥ 9,950
5日内发货
1 mg
¥ 15,600
5日内发货
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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
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产品介绍

生物活性
产品描述
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant is expressed in E. coli. The accession number is O14763.
生物活性
Fully biologically active when compared to standard. rHusTRAIL-R2 reduced the production of LPS-induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC. In this assay, endogenous TRAIL is induced during a 24 hour exposure to LPS (10 ng/ml) but in the presence of rHusTRAIL-R2, TRAIL-induced TNF is suppressed.
研究背景
Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 (TRAIL-R2) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.1 The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells.2 TRAIL-R2 has been shown to be associated with a decrease in the survival rates of breast cancer patients.
种属
Human
表达系统
E. coli
标签Tag Free
蛋白编号O14763
蛋白构建Glu52-Ser183
蛋白纯度
> 97% as determined by SDS-PAGE; > 97% as determined by HPLC
缓冲液Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
复溶方法It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml.
别名ZTNFR9, Tumor necrosis factor receptor superfamily member 10B, TRICKB, TRICK2B, TRICK2A, TRICK2, TRAIL-R2, TRAILR2, TRAIL receptor 2, TNFRSF10B, TNF-related apoptosis-inducing ligand receptor 2, KILLER/DR5, KILLER, DR5, Death receptor 5, CD262
内毒素< 1 EU/μg of protein by LAL method
化学信息
分子量14.8 kDa (Predicted)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.

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