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TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant is expressed in E. coli. The accession number is O14763.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 576 | 6-8日内发货 | |
| 10 μg | ¥ 945 | 6-8日内发货 | |
| 20 μg | ¥ 1,370 | 5日内发货 | |
| 50 μg | ¥ 2,260 | 5日内发货 | |
| 100 μg | ¥ 3,520 | 5日内发货 | |
| 200 μg | ¥ 5,480 | 5日内发货 | |
| 500 μg | ¥ 9,950 | 5日内发货 | |
| 1 mg | ¥ 15,600 | 5日内发货 |
| 生物活性 | Fully biologically active when compared to standard. rHusTRAIL-R2 reduced the production of LPS-induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC. In this assay, endogenous TRAIL is induced during a 24 hour exposure to LPS (10 ng/ml) but in the presence of rHusTRAIL-R2, TRAIL-induced TNF is suppressed. |
| 产品描述 | TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant is expressed in E. coli. The accession number is O14763. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | Tag Free |
| 蛋白编号 | O14763 |
| 别名 | ZTNFR9,Tumor necrosis factor receptor superfamily member 10B,TRICKB,TRICK2B,TRICK2A,TRICK2,TRAIL-R2,TRAILR2,TRAIL receptor 2,TNFRSF10B,TNF-related apoptosis-inducing ligand receptor 2,KILLER/DR5,KILLER,DR5,Death receptor 5,CD262 |
| 蛋白构建 | Glu52-Ser183 |
| 蛋白纯度 | > 97% as determined by SDS-PAGE; > 97% as determined by HPLC |
| 分子量 | 14.8 kDa (Predicted) |
| 内毒素 | < 1 EU/μg of protein by LAL method |
| 缓冲液 | Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4. |
| 复溶方法 | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. |
| 存储 | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 (TRAIL-R2) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.1 The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells.2 TRAIL-R2 has been shown to be associated with a decrease in the survival rates of breast cancer patients. |