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Anti-GRIM19 Antibody (2M560)

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Anti-GRIM19 Antibody (2M560)
产品编号 TMAC-01713
别名 RGD1565358, NDUFA13, NDUAD_HUMAN, NADH-ubiquinone oxidoreductase B16.6 subunit, NADH ubiquinone oxidoreductase B16.6 subunit, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13, GRIM-19, Gene associated with retinoic interferon induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 protein, Gene associated with retinoic and IFN-induced mortality 19 protein, FLJ59191, FLJ58045, Complex I-B16.6, CI-B16.6, CGI39 protein, CGI-39, Cell death regulatory protein GRIM-19, Cell death regulatory protein, CDA016, B16.6, AU022060, 2700054G14Rik

Anti-GRIM19 Antibody (2M560) 是一种 Rabbit 抗体，靶向 GRIM19。Anti-GRIM19 Antibody (2M560) 可用于 WB,IHC,ICC。

Anti-GRIM19 Antibody (2M560)

Anti-GRIM19 Antibody (2M560)

Rating icon 还可以
Anti-GRIM19 Antibody (2M560)
产品编号 TMAC-01713 别名 RGD1565358, NDUFA13, NDUAD_HUMAN, NADH-ubiquinone oxidoreductase B16.6 subunit, NADH ubiquinone oxidoreductase B16.6 subunit, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13, GRIM-19, Gene associated with retinoic interferon induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 protein, Gene associated with retinoic and IFN-induced mortality 19 protein, FLJ59191, FLJ58045, Complex I-B16.6, CI-B16.6, CGI39 protein, CGI-39, Cell death regulatory protein GRIM-19, Cell death regulatory protein, CDA016, B16.6, AU022060, 2700054G14Rik

Anti-GRIM19 Antibody (2M560) 是一种 Rabbit 抗体，靶向 GRIM19。Anti-GRIM19 Antibody (2M560) 可用于 WB,IHC,ICC。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-GRIM19 Antibody (2M560) is a Rabbit antibody targeting GRIM19. Anti-GRIM19 Antibody (2M560) can be used in WB,IHC,ICC.
别名RGD1565358, NDUFA13, NDUAD_HUMAN, NADH-ubiquinone oxidoreductase B16.6 subunit, NADH ubiquinone oxidoreductase B16.6 subunit, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13, GRIM-19, Gene associated with retinoic interferon induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 protein, Gene associated with retinoic and IFN-induced mortality 19 protein, FLJ59191, FLJ58045, Complex I-B16.6, CI-B16.6, CGI39 protein, CGI-39, Cell death regulatory protein GRIM-19, Cell death regulatory protein, CDA016, B16.6, AU022060, 2700054G14Rik
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of GRIM19 on MCF-7 cell using anti-GRIM19 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using anti-GRIM19 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-GRIM19 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-GRIM19 antibody. Counter stained with hematoxylin.
5. ICC staining GRIM19 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
IHC
ICC
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The GRIM family of proteins appear to be novel types of tumor suppressors. Grim19, which stands for gene associated with retinoic-interferon-induced mortality 19 protein, is also designated cell death-regulatory protein Grim-19 or NADH dehydrogenase ubiquinone 1 alpha subcomplex subunit 13. The Grim19 protein plays two roles within the cell. As a member of the interferon-beta and retinoic acid-induced pathway of cell death, Grim19 induces apoptosis. As part of the mitochondrial complex I, Grim19 is essential for its assembly and electron transfer activity. It transfers electrons to the respiratory chain from NADH and plays a role in the interferon/all-trans-retinoic acid (IFN/RA) cell death pathway. It localizes primarily to the mitochondrion, but may translocate to the nucleus upon IFN/RA treatment. Grim19 may also be useful as a biological marker or target for drug development.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: human GRIM19 aa 1-150
抗原种属
human
Uniprot ID
Q9P0J0
化学信息
分子量Theoretical: 17 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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