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Anti-RhoA Antibody-FITC (4W246)

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产品编号 TMAY-02350F
别名 RHOH12, RHO12, ras homolog family member A, ARHA, ARH12

Anti-RhoA Antibody-FITC (4W246) 是一种 FITC-conjugated Rabbit 抗体,靶向 RhoA。Anti-RhoA Antibody-FITC (4W246) 可用于 FCM。

Anti-RhoA Antibody-FITC (4W246)

Anti-RhoA Antibody-FITC (4W246)

Rating icon 还可以
产品编号 TMAY-02350F 别名 RHOH12, RHO12, ras homolog family member A, ARHA, ARH12

Anti-RhoA Antibody-FITC (4W246) 是一种 FITC-conjugated Rabbit 抗体,靶向 RhoA。Anti-RhoA Antibody-FITC (4W246) 可用于 FCM。

规格价格库存数量
25 T
¥ 885
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100 T
¥ 1,795
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产品介绍

生物活性
产品描述
Anti-RhoA Antibody-FITC (4W246) is a FITC-conjugated Rabbit antibody targeting RhoA. Anti-RhoA Antibody-FITC (4W246) can be used in FCM.
别名RHOH12, RHO12, ras homolog family member A, ARHA, ARH12
Ig Type
Monoclonal Rabbit IgG
克隆号
4W246
交叉反应
Human
验证活性
Flow cytometric analysis of Human RHOA expression in HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with FITC Rabbit anti-Human RHOA. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human RhoA (rh RhoA; TMPY-01958; P61586-1; Met1-Leu193) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景Transforming protein RhoA, also known as Rho cDNA clone 12, Ras homolog gene family member A, RHOA and ARH12, is a cell membrane and cytoplasm protein that belongs to the small GTPase superfamily and Rho family. The Rho family of small GTPases plays a key role in the dynamic regulation of the actin cytoskeleton that underlies various important cellular functions such as shape changes, migration, and polarity. RHOA / ARH12 is part of a larger family of related proteins known as the Ras superfamily; proteins involved in the regulation and timing of cell division. RHOA / ARH12 is a small GTPase protein known to regulate the actin cytoskeleton in the formation of stress fibers. It acts upon two known effector proteins: ROCK1 (Rho-associated, coiled-coil containing protein kinase 1) and DIAPH1 ( diaphanous homolog 1 (Drosophila) ). RHOA / ARH12 regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. RHOA / ARH12 serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. RHOA / ARH12 may be an activator of PLCE1. It is activated by ARHGEF2, which promotes the exchange of GDP for GTP.
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Human RhoA protein (TMPY-01958)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
运输方式Shipping with blue ice.

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