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Anti-eRF3/GSPT1 Antibody (1V576) 是一种 Rabbit 抗体,靶向 eRF3/GSPT1。Anti-eRF3/GSPT1 Antibody (1V576) 可用于 WB。
Anti-eRF3/GSPT1 Antibody (1V576) 是一种 Rabbit 抗体,靶向 eRF3/GSPT1。Anti-eRF3/GSPT1 Antibody (1V576) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-eRF3/GSPT1 Antibody (1V576) is a Rabbit antibody targeting eRF3/GSPT1. Anti-eRF3/GSPT1 Antibody (1V576) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 1V576 |
| 反应种属 | Human (predicted:Mouse,Rat) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasmic. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | eRF3a is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94% sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. |
| 免疫原 | KLH conjugated synthetic peptide: human eRF3/GSPT1 |
| 基因名称 | GSPT1 |
| 基因ID | |
| 蛋白名称 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A |
| 功能 | Translation termination in eukaryotes is governed by two proteins, belonging to the class-1 (eRF1) and class-2 (eRF3) polypeptide release factors. eRF3/GSPT1 is involved in regulation of mammalian cell growth and belongs to the GTP-binding elongation factor family (ERF3 subfamily). eRF3 catalyzes hydrolysis of GTP to GDP and inorganic phosphate in the ribosome in the absence of mRNA, tRNA, aminoacyl-tRNA and peptidyl-tRNA. |
| 分子量 | Theoretical: 56 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |