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Anti-Phospho-eNOS (Ser1177) Antibody (4B383)

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产品编号 TMAB-10646

Anti-Phospho-eNOS (Ser1177) Antibody (4B383) 是一种 Rabbit 抗体,靶向 Phospho-eNOS (Ser1177)。Anti-Phospho-eNOS (Ser1177) Antibody (4B383) 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-eNOS (Ser1177) Antibody (4B383)

Anti-Phospho-eNOS (Ser1177) Antibody (4B383)

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10646

Anti-Phospho-eNOS (Ser1177) Antibody (4B383) 是一种 Rabbit 抗体,靶向 Phospho-eNOS (Ser1177)。Anti-Phospho-eNOS (Ser1177) Antibody (4B383) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 790
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50 μL
¥ 1,395
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100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-eNOS (Ser1177) Antibody (4B383) is a Rabbit antibody targeting Phospho-eNOS (Ser1177). Anti-Phospho-eNOS (Ser1177) Antibody (4B383) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
4B383
交叉反应
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.
组织特异性Platelets, placenta, liver and kidney.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Nitric oxide synthase NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti tumor and anti pathogenic activities. NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS); inducible NOS (iNOS) or macrophage NOS (mNOS); and endothelial NOS (eNOS).
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human eNOS around the phosphorylation site of Ser1177:
抗原种属
Human
基因名称
NOS3
基因ID
蛋白名称
Nitric oxide synthase, endothelial
Uniprot ID
功能
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
化学信息
分子量Theoretical: 133 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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