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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PAG1 Antibody (2D54)

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货号 TMAB-09927

Anti-PAG1 Antibody (2D54) 是一种 Rabbit 抗体，靶向 PAG1。Anti-PAG1 Antibody (2D54) 可用于 WB,IHC-P,IHC-Fr,IP,FCM,IF,ICC/IF。

Anti-PAG1 Antibody (2D54)

Anti-PAG1 Antibody (2D54)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09927

Anti-PAG1 Antibody (2D54) 是一种 Rabbit 抗体，靶向 PAG1。Anti-PAG1 Antibody (2D54) 可用于 WB,IHC-P,IHC-Fr,IP,FCM,IF,ICC/IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-PAG1 Antibody (2D54) is a Rabbit antibody targeting PAG1. Anti-PAG1 Antibody (2D54) can be used in WB,IHC-P,IHC-Fr,IP,FCM,IF,ICC/IF.
Ig Type
IgG
克隆号
2D54
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIPFCMIFICC/IF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IP: 1:20-50; FCM: 1:50-100; IF: 1:100-500; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Present in lipid rafts.
组织特异性Ubiquitously expressed. Present in germinal center B-cells, plasma cells, T-cells, monocytes and platelets (at protein level).
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
抗原信息
免疫原
A synthesized peptide: human PAG1
抗原种属
Human
基因名称
PAG1
基因ID
55824
蛋白名称
phosphoprotein associated with glycosphingolipid-enriched microdomains 1
Uniprot ID
Q9NWQ8
功能
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
化学信息
分子量Theoretical: 47 kDa. Actual: 80 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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