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Anti-Phospho-Alpha-Synuclein (Ser129) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Alpha-Synuclein (Ser129)。Anti-Phospho-Alpha-Synuclein (Ser129) Polyclonal Antibody 可用于 WB,IHC,IF。
Anti-Phospho-Alpha-Synuclein (Ser129) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Alpha-Synuclein (Ser129)。Anti-Phospho-Alpha-Synuclein (Ser129) Polyclonal Antibody 可用于 WB,IHC,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-Alpha-Synuclein (Ser129) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Alpha-Synuclein (Ser129). Anti-Phospho-Alpha-Synuclein (Ser129) Polyclonal Antibody can be used in WB,IHC,IF. |
别名 | p-Alpha-Synuclein (Ser129), p-Alpha-Synuclein (S129), Alpha-Synuclein (p-Ser129), Alpha-Synuclein (p-S129) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from mouse brain tissue using a-Synuclein (Phospho-Ser129) Antibody TMAC-00290 (Lane 2) and the same antibody preincubated with blocking peptide (Lane1). 2. Immunohistochemistry analysis of paraffin-embedded human brain, using Synuclein (Phospho-Ser129) Antibody. The picture on the right is blocked with the phospho peptide. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 129 (M-P-S(p)-E-E) derived from Human a-Synuclein |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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