Cefoperazone sodium salt

Name: Cefoperazone sodium salt
Brand: TargetMol
SKU: T1218
Rating: 4.5 (1 reviews)

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很棒

纯度: 99.54%

货号 T1218Cas号 62893-20-3

别名 头孢哌酮钠, CP 52640-2, Cefoperazone sodium

Cefoperazone sodium salt (CP 52640-2) 是一种半合成的头孢菌素，具有广谱抗菌活性。

Cefoperazone sodium salt

一键复制产品信息

很棒

纯度: 99.54%

货号 T1218 别名 头孢哌酮钠, CP 52640-2, Cefoperazone sodiumCas号 62893-20-3

Cefoperazone sodium salt (CP 52640-2) 是一种半合成的头孢菌素，具有广谱抗菌活性。

规格	价格	库存
500 mg	¥ 198	待询
1 g	¥ 328	待询
1 mL x 10 mM (in DMSO)	¥ 150	现货

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纯度: 99.54%

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产品介绍

Cefoperazone sodium salt AI Summary

Cefoperazone sodium salt demonstrates multifunctional bioactivity, showcasing its potential as an antiviral, trypanocidal, and antibacterial agent. It inhibits the entry of the Ebola virus with AC50 values ranging from 0.3162 µM to 15.85 µM across various assay screenings, indicating its potential for development as an antiviral therapeutic. The compound also exhibits significant trypanocidal activity against the trypomastigote stage of Trypanosoma cruzi, causing 71.0% lysis at 50 µg/mL after 24 hours in NIH mouse blood, with an LC50 value of 23.0 µg/mL. Its efficacy extends to Trypanosoma cruzi INC-5 and NINOA strains, with LC50 values of 23.0 and 25.8 µg/mL, respectively. Additionally, Cefoperazone sodium salt inhibits Trypanosoma cruzi trans-sialidase activity by 10.1% at 1 mM. Furthermore, it exhibits potent antibacterial activity against strains such as methicillin-resistant Staphylococcus aureus, Staphylococcus aureus, Listeria monocytogenes, Pseudomonas aeruginosa, and Escherichia coli, with minimum inhibitory concentrations (MIC) ranging from 0.125 to 8.0 µg/mL, though it is less effective against cephalosporin-resistant Escherichia coli with an MIC greater than 128.0 µg/mL..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Cefoperazone sodium salt (CP 52640-2) is broad-spectrum cephalosporin with a tetrazolyl moiety, used to treat Pseudomonas infections.
靶点活性	[3H]-E217βG (rMrp2-mediated):199 μM
别名	头孢哌酮钠, CP 52640-2, Cefoperazone sodium

化学信息

分子量	667.65
分子式	C₂₅H₂₆N₉NaO₈S₂
CAS No.	62893-20-3
Smiles	N12[C@@H]([C@@H](C2=O)NC(=O)[C@@H](c2ccc(cc2)O)NC(=O)N2C(=O)C(=O)N(CC2)CC)SCC(=C1C(=O)[O-])CSc1n(nnn1)C.[Na+]
密度	no data available

储存&溶解度

存储

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 45 mg/mL (67.4 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (3 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.4978 mL	7.4890 mL	14.9779 mL	74.8895 mL
5 mM	0.2996 mL	1.4978 mL	2.9956 mL	14.9779 mL
10 mM	0.1498 mL	0.7489 mL	1.4978 mL	7.4890 mL
20 mM	0.0749 mL	0.3744 mL	0.7489 mL	3.7445 mL
50 mM	0.0300 mL	0.1498 mL	0.2996 mL	1.4978 mL