Tat-peptide 190-208 is a Tat-tagged cell-penetrating fusion peptide that corresponds to residues 190-208 of rat G3BP1. The Tat sequence from HIV, positioned at the least conserved end of the sequence, facilitates cell permeability. Tat-peptide 190-208 enhances axonal growth and increases the number of axons per neuron, potentially demonstrating intrinsic axonal mechanisms. It may also be employed for ischemic protection during endovascular repair of intracranial aneurysms.