规格

价格

库存

数量

10 mg

待询

50 mg

待询

生物活性

产品描述

Tat-peptide 190-208 is a Tat-tagged cell-penetrating fusion peptide that corresponds to residues 190-208 of rat G3BP1. The Tat sequence from HIV, positioned at the least conserved end of the sequence, facilitates cell permeability. Tat-peptide 190-208 enhances axonal growth and increases the number of axons per neuron, potentially demonstrating intrinsic axonal mechanisms. It may also be employed for ischemic protection during endovascular repair of intracranial aneurysms.

体外活性

Tat-peptide 190-208（10 μM、20 μM；24 小时）在分离的 DRG 培养物中可增加轴突长度为 10 μM，在 iMotor 神经元中则增加为 20 μM。Tat-peptide 190-208（10 μM；3 天）还提高了每个神经元所延伸出的轴突总数。