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TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi)

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货号 TMPK-00038

别名 TSLP, thymic stromal lymphopoietin

Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.7 kDa and the accession number is Q969D9-1.

TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi)

TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi)

一键复制产品信息
Rating icon 还可以
SPR兼容缓冲液
货号 TMPK-00038 别名 TSLP, thymic stromal lymphopoietin

Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.7 kDa and the accession number is Q969D9-1.

规格价格库存数量
5 μg
¥ 343
6-8日内发货
10 μg
¥ 549
6-8日内发货
20 μg
¥ 898
5日内发货
50 μg
¥ 1,760
5日内发货
100 μg
¥ 2,960
5日内发货
200 μg
¥ 5,350
5日内发货
500 μg
¥ 11,800
5日内发货
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产品介绍


生物活性
产品描述
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.7 kDa and the accession number is Q969D9-1.
生物活性
Immobilized Human TSLP (R127A,R130A) , His Tag at 0.5μg/ml (100μl/Well). Dose response curve for Anti-Human TSLP Ab., hFc Tag with the EC50 of 62.6ng/ml determined by ELISA.
研究背景
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells.
种属
Human
表达系统
HEK293 Cells
标签C-His-Avi
蛋白编号Q969D9-1
蛋白构建Tyr29-Gln159(R127A,R130A)
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名TSLP, thymic stromal lymphopoietin
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量17.7 kDa (predicted). Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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技术支持

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