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Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-HER2/ERBB2 (Tyr1139)。Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody 可用于 IHC-P,IF(paraffin section),WB。
Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-HER2/ERBB2 (Tyr1139)。Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody 可用于 IHC-P,IF(paraffin section),WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,230 | 5日内发货 |
产品描述 | Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HER2/ERBB2 (Tyr1139). Anti-Phospho-HER2/ERBB2 (Tyr1139) Polyclonal Antibody can be used in IHC-P,IF(paraffin section),WB. |
别名 | p-HER2/ERBB2 (Y1139), p-HER2/ERBB2 (Tyr1139), HER2/ERBB2 (p-Y1139), HER2/ERBB2 (p-Tyr1139) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
应用 | |
推荐剂量 | IHC-P 1:50-200 WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | erb-b2 receptor tyrosine kinase 2(ERBB2) Homo sapiens This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding d |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human HER2 around the phosphorylation site of Tyr1139 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 180 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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