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ARID4B Protein, Human, Recombinant (His)

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货号 TMPH-00989

别名 SAP180, Retinoblastoma-binding protein 1-like 1, RBP1L1, RBBP1L1, Histone deacetylase complex subunit SAP180, Breast cancer-associated antigen BRCAA1, BRCAA1, AT-rich interactive domain-containing protein 4B, ARID4B, ARID domain-containing protein 4B, 180 kDa Sin3-associated polypeptide (Sin3-associated polypeptide p180)

ARID4B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.8 kDa and the accession number is Q4LE39.

ARID4B Protein, Human, Recombinant (His)
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ARID4B Protein, Human, Recombinant (His)

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货号 TMPH-00989 别名 SAP180, Retinoblastoma-binding protein 1-like 1, RBP1L1, RBBP1L1, Histone deacetylase complex subunit SAP180, Breast cancer-associated antigen BRCAA1, BRCAA1, AT-rich interactive domain-containing protein 4B, ARID4B, ARID domain-containing protein 4B, 180 kDa Sin3-associated polypeptide (Sin3-associated polypeptide p180)

ARID4B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.8 kDa and the accession number is Q4LE39.

规格价格库存数量
5 μg
¥ 825
20日内发货
10 μg
¥ 1,360
20日内发货
20 μg
¥ 2,290
20日内发货
50 μg
¥ 3,460
20日内发货
100 μg
¥ 4,750
20日内发货
200 μg
¥ 6,830
20日内发货
500 μg
¥ 10,800
20日内发货
1 mg
¥ 16,000
20日内发货
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产品介绍


生物活性
产品描述
ARID4B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.8 kDa and the accession number is Q4LE39.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. Plays a role in the regulation of epigenetic modifications at the PWS/AS imprinting center near the SNRPN promoter, where it might function as part of a complex with RB1 and ARID4A. Involved in spermatogenesis, together with ARID4A, where it functions as a transcriptional coactivator for AR (androgen receptor) and enhances expression of genes required for sperm maturation. Regulates expression of the tight junction protein CLDN3 in the testis, which is important for integrity of the blood-testis barrier. Plays a role in myeloid homeostasis where it regulates the histone methylation state of bone marrow cells and expression of various genes involved in hematopoiesis. May function as a leukemia suppressor.
种属
Human
表达系统
E. coli
标签N-6xHis
蛋白编号Q4LE39
氨基酸序列KQIDELLGKVVCVDYISLDKKKALWFPALVVCPDCSDEIAVKKDNILVRSFKDGKFTSVPRKDVHEITSDTAPKPDAVLKQAFEQALEFHKSRTIPANWKTELKEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEEIEPFPEERENFLQQLYKFMEDRGTPINKRPVLGYRNLNLFKLFRLVHKLGGFDNIESGAVWKQVYQDLGIPVLNSAAGYNVKCAYKKYLYGFEEYCRSANIEFQMALPEKVVNK
蛋白构建167-415 aa
蛋白纯度
> 85% as determined by SDS-PAGE.
缓冲液Tris-based buffer, 50% glycerol
复溶方法A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名SAP180, Retinoblastoma-binding protein 1-like 1, RBP1L1, RBBP1L1, Histone deacetylase complex subunit SAP180, Breast cancer-associated antigen BRCAA1, BRCAA1, AT-rich interactive domain-containing protein 4B, ARID4B, ARID domain-containing protein 4B, 180 kDa Sin3-associated polypeptide (Sin3-associated polypeptide p180)
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量32.8 kDa (predicted)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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