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Anti-Cystatin A Antibody (3Z824) 是一种 Mouse 抗体,靶向 Cystatin A。Anti-Cystatin A Antibody (3Z824) 可用于 IHC-P。
Anti-Cystatin A Antibody (3Z824) 是一种 Mouse 抗体,靶向 Cystatin A。Anti-Cystatin A Antibody (3Z824) 可用于 IHC-P。
产品描述 | Anti-Cystatin A Antibody (3Z824) is a Mouse antibody targeting Cystatin A. Anti-Cystatin A Antibody (3Z824) can be used in IHC-P. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 3Z824 |
交叉反应 | Human |
验证活性 | 1. Immunochemical staining of human CSTA in human tonsil with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CSTA in human skin with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human CSTA in human malignant melanoma with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
应用 | IHC-P |
推荐剂量 | IHC-P: 1:50-1:200 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cystatin A / CSTA (rh Cystatin A / CSTA; TMPY-02077; P01040; Ile2-Phe98). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Cystatin-A, also known as Cystatin-AS, Stefin-A and CSTA, is a cytoplasm protein which belongs to thecystatin family. Cystatin-A / CSTA is a cysteine proteinase inhibitor with a molecular mass of 11 kDa, and is located mainly in the keratohyaline granules of the stratum granulosum and the cornified envelope of the stratum corneum in the epidermis. The cystatins are a family of cysteine protease inhibitors with homology to chicken cystatin. Cystatins are physiological inhibitors of cysteine proteinases which are widely distributed in human tissues and fluids. Cystatins typically comprise about 115 amino acids, are largely acidic, contain four conserved cysteine residues known to form two disulfide bonds. Cystatins may be glycosylated and / or phosphorylated, with similarity to fetuins, kininogens, stefins, histidine-rich glycoproteins and cystatin-related proteins. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired inhibitory activity. Cystatins mainly inhibit peptidases belonging to peptidase families C1 (papain family) and C13 (legumain family). |
偶联 | Unconjugated |
免疫原 | Recombinant Human Cystatin A / CSTA protein (TMPY-02077) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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