Name: Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3)
Brand: TargetMol
SKU: T9901A-189
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

¥ 1,600

4-6周

5 mg

¥ 3,520

4-6周

10 mg

待询

4-6周

生物活性

产品描述	Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3) is a rat-derived agonistic antibody targeting mouse 4-1BB/CD137 that can stimulate 4-1BB signaling and induce T cell-mediated anti-tumor immunity. Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3) can be used in research on cancer, infection, immunology, and neurological diseases, such as glioblastoma and retroviral infection .
体内活性	Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3) 与 anti-PD-1 联用（200 μg，腹腔注射，第 9 天起每 3 天 1 次）可改善胶质母细胞瘤模型中肿瘤浸润淋巴细胞功能，延长 CT2A 荷瘤小鼠生存期 [1]。 Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3) （100 μg，腹腔注射，感染后第 4 天起隔日 1 次）可轻度增加 Friend 逆转录病毒感染小鼠体内病毒特异性 CD4+ T 细胞数量，并显著提升颗粒酶 B（GzmB）表达水平 [2]。
别名	抗小鼠4-1BB/CD137抗体(LOB12.3)
克隆号	LOB12.3
反应种属	Mouse
应用	ELISA FCM Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型	Rat IgG1 kappa
推荐同型对照	Rat IgG1 kappa, Isotype Control

偶联与修饰

偶联	Unconjugated

抗原信息

化学信息

储存&溶解度

存储	store at low temperature \| -20°C for 2 years, 4°C for 1 year \| Shipping with blue ice.

Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3)