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Anti-PTH1R Antibody (6S56)

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产品编号 TMAY-02290

Anti-PTH1R Antibody (6S56) 是一种 Rabbit 抗体,靶向 PTH1R。Anti-PTH1R Antibody (6S56) 可用于 ELISA。

Anti-PTH1R Antibody (6S56)

Anti-PTH1R Antibody (6S56)

Rating icon 还可以
产品编号 TMAY-02290

Anti-PTH1R Antibody (6S56) 是一种 Rabbit 抗体,靶向 PTH1R。Anti-PTH1R Antibody (6S56) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-PTH1R Antibody (6S56) is a Rabbit antibody targeting PTH1R. Anti-PTH1R Antibody (6S56) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
6S56
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human PTH1R / PTHR1 (rh PTH1R / PTHR1; TMPY-02236; Q03431; Met1-Gly188).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Parathyroid hormone / parathyroid hormone-related peptide receptor, also known as PTH / PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor, PTH1R and PTHR, is a multi-pass membrane protein which belongs to the G-protein coupled receptor 2 family. PTH1R is expressed in most tissues. It is most abundant in kidney, bone and liver. PTH1R is expressed in high levels in bone and kidney and regulates calcium ion homeostasis through activation of adenylate cyclase and phospholipase C. In bone, PTH1R is expressed on the surface of osteoblasts. When the receptor is activated, these cells in turn stimulate osteoclasts to ultimately increase the resorption rate. PTH1R is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of PTH1R is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in PTH1R are the cause of Jansen metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), enchondromatosis multiple (ENCHOM), Eiken skeletal dysplasia (EISD) and primary failure of tooth eruption (PFE).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human PTH1R / PTHR1 protein (TMPY-02236)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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