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Anti-Phospho-PAK2 (Ser141) Polyclonal Antibody 3
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还可以产品编号 TMAB-11105
Anti-Phospho-PAK2 (Ser141) Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 Phospho-PAK2 (Ser141)。Anti-Phospho-PAK2 (Ser141) Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,IF。
Anti-Phospho-PAK2 (Ser141) Polyclonal Antibody 3
Anti-Phospho-PAK2 (Ser141) Polyclonal Antibody 3
一键复制产品信息 还可以产品编号 TMAB-11105
Anti-Phospho-PAK2 (Ser141) Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 Phospho-PAK2 (Ser141)。Anti-Phospho-PAK2 (Ser141) Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
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| 产品描述 | Anti-Phospho-PAK2 (Ser141) Polyclonal Antibody 3 is a Rabbit antibody targeting Phospho-PAK2 (Ser141). Anti-Phospho-PAK2 (Ser141) Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 交叉反应 | Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm and Nucleus. Cytoplasm > perinuclear region. Membrane. Interaction with ARHGAP10 probably changes PAK-2p34 location to cytoplasmic perinuclear region. Myristoylation changes PAK-2p34 location to the membrane. |
| 组织特异性 | Ubiquitously expressed. Higher levels seen in skeletal muscle, ovary, thymus and spleen. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human PAK2 around the phosphorylation site of Ser141 |
| 抗原种属 | Human |
| 基因名称 | PAK2 |
| 基因ID | |
| 蛋白名称 | Serine/threonine-protein kinase PAK 2 |
| Uniprot ID | |
| 功能 | The activated kinase acts on a variety of targets. Phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. Full length PAK 2 stimulates cell survival and cell growth. The process is, at least in part, mediated by phosphorylation and inhibition of pro-apoptotic BAD. Caspase-activated PAK-2p34 is involved in cell death response, probably involving the JNK signaling pathway. Cleaved PAK-2p34 seems to have a higher activity than the CDC42-activated form. |
| 分子量 | Theoretical: 23/35/58 kDa. |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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