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Anti-PGC1 alpha/beta Antibody (4L458) 是一种 Rabbit 抗体,靶向 PGC1 alpha/beta。Anti-PGC1 alpha/beta Antibody (4L458) 可用于 WB。
Anti-PGC1 alpha/beta Antibody (4L458) 是一种 Rabbit 抗体,靶向 PGC1 alpha/beta。Anti-PGC1 alpha/beta Antibody (4L458) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-PGC1 alpha/beta Antibody (4L458) is a Rabbit antibody targeting PGC1 alpha/beta. Anti-PGC1 alpha/beta Antibody (4L458) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 4L458 |
| 反应种属 | Mouse,Rat (predicted:Human) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Heart, skeletal muscle, liver and kidney. Expressed at lower levels in brain and pancreas and at very low levels in the intestine and white adipose tissue. In skeletal muscle, levels were lower in obese than in lean subjects and fasting induced a 2-fold increase in levels in the skeletal muscle in obese subjects. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Transcriptional coactivator for steroid receptors and nuclear receptors.Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter.Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. |
| 免疫原 | A synthesized peptide: human PGC1 alpha |
| 抗原种属 | Human |
| 基因名称 | PPARGC1A |
| 基因ID | |
| 蛋白名称 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha |
| Uniprot ID | |
| 功能 | Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. |
| 分子量 | Theoretical: 91, 113 kDa. Actual: 113 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |