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Anti-CCR3 Polyclonal Antibody

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产品编号 TMAB-00324

别名 Probable C-C chemokine receptor type 3, MIP-1 alpha RL2, MIP1 alpha RL2, MIP-1 alpha receptor like-2, MGC102841, Macrophage inflammatory protein 1-alpha receptor-like 2, Macrophage inflammatory protein 1 alpha receptor like 2, Eotaxin receptor, Eosinophil eotaxin receptor, Eosinophil CC chemokine receptor 3, CMKBR3, CMKBR1L2, CMKBR 3, CMKB R3, CKR3, CKR 3, CK R3, Chemokine(CC) receptor 1 like 2, Chemokine(C-C motif) receptor 3, Chemokine receptor 3, Chemokine CC motif receptor 3, CD193 antigen, CD193, CD 193, CCR-3, CCR3, CCR 3, CC-CKR-3, CCCKR3, CC R3, C-C CKR-3, CC CKR 3, C-C chemokine receptor type 3, CC chemokine receptor type 3, CC chemokine receptor 3, C C CKR 3, B chemokine receptor

Anti-CCR3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CCR3。Anti-CCR3 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

Anti-CCR3 Polyclonal Antibody

Anti-CCR3 Polyclonal Antibody

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产品编号 TMAB-00324 别名 Probable C-C chemokine receptor type 3, MIP-1 alpha RL2, MIP1 alpha RL2, MIP-1 alpha receptor like-2, MGC102841, Macrophage inflammatory protein 1-alpha receptor-like 2, Macrophage inflammatory protein 1 alpha receptor like 2, Eotaxin receptor, Eosinophil eotaxin receptor, Eosinophil CC chemokine receptor 3, CMKBR3, CMKBR1L2, CMKBR 3, CMKB R3, CKR3, CKR 3, CK R3, Chemokine(CC) receptor 1 like 2, Chemokine(C-C motif) receptor 3, Chemokine receptor 3, Chemokine CC motif receptor 3, CD193 antigen, CD193, CD 193, CCR-3, CCR3, CCR 3, CC-CKR-3, CCCKR3, CC R3, C-C CKR-3, CC CKR 3, C-C chemokine receptor type 3, CC chemokine receptor type 3, CC chemokine receptor 3, C C CKR 3, B chemokine receptor

Anti-CCR3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CCR3。Anti-CCR3 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,160
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100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品描述
Anti-CCR3 Polyclonal Antibody is a Rabbit antibody targeting CCR3. Anti-CCR3 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
别名Probable C-C chemokine receptor type 3, MIP-1 alpha RL2, MIP1 alpha RL2, MIP-1 alpha receptor like-2, MGC102841, Macrophage inflammatory protein 1-alpha receptor-like 2, Macrophage inflammatory protein 1 alpha receptor like 2, Eotaxin receptor, Eosinophil eotaxin receptor, Eosinophil CC chemokine receptor 3, CMKBR3, CMKBR1L2, CMKBR 3, CMKB R3, CKR3, CKR 3, CK R3, Chemokine(CC) receptor 1 like 2, Chemokine(C-C motif) receptor 3, Chemokine receptor 3, Chemokine CC motif receptor 3, CD193 antigen, CD193, CD 193, CCR-3, CCR3, CCR 3, CC-CKR-3, CCCKR3, CC R3, C-C CKR-3, CC CKR 3, C-C chemokine receptor type 3, CC chemokine receptor type 3, CC chemokine receptor 3, C C CKR 3, B chemokine receptor
Ig Type
IgG
交叉反应
Human,Rat (predicted:Mouse,Dog,Cow)
验证活性
1. Tissue/cell: rat colitis tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-CCR3 Polyclonal Antibody, Unconjugated (TMAB-00324) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
2. Tissue/cell: human breast carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-CCR3 Polyclonal Antibody, Unconjugated (TMAB-00324) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性In eosinophils as well as trace amounts in neutrophils and monocytes.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3(CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants encoding the same protein have been described.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CCR3
抗原种属
Human
基因名称
CCR3
基因ID
1232
蛋白名称
C-C chemokine receptor type 3
Uniprot ID
P51677
研究领域
HIV-related,Beta Chemokine Rec. (CCR),GPCR
功能
Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
化学信息
分子量Theoretical: 41 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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