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Anti-Granzyme B Antibody (7J12)

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货号 TMAB-06755

Anti-Granzyme B Antibody (7J12) 是一种 Rabbit 抗体,靶向 Granzyme B。Anti-Granzyme B Antibody (7J12) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Granzyme B Antibody (7J12)

Anti-Granzyme B Antibody (7J12)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06755

Anti-Granzyme B Antibody (7J12) 是一种 Rabbit 抗体,靶向 Granzyme B。Anti-Granzyme B Antibody (7J12) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-Granzyme B Antibody (7J12) is a Rabbit antibody targeting Granzyme B. Anti-Granzyme B Antibody (7J12) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
7J12
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic granule. Note=Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液PBS, Glycerol, BSA.
浓度1mg/ml
研究背景Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
A synthesized peptide: human Granzyme B
抗原种属
Human
基因名称
GZMB
基因ID
蛋白名称
Granzyme B
Uniprot ID
功能
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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