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Anti-Granzyme B Antibody (7J12) 是一种 Rabbit 抗体,靶向 Granzyme B。Anti-Granzyme B Antibody (7J12) 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-Granzyme B Antibody (7J12) 是一种 Rabbit 抗体,靶向 Granzyme B。Anti-Granzyme B Antibody (7J12) 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 785 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-Granzyme B Antibody (7J12) is a Rabbit antibody targeting Granzyme B. Anti-Granzyme B Antibody (7J12) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 克隆号 | 7J12 |
| 反应种属 | Human |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasmic granule. Note=Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | PBS, Glycerol, BSA. |
| 浓度 | 1mg/ml |
| 研究背景 | Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008] |
| 免疫原 | A synthesized peptide: human Granzyme B |
| 抗原种属 | Human |
| 基因名称 | GZMB |
| 基因ID | |
| 蛋白名称 | Granzyme B |
| Uniprot ID | |
| 功能 | This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. |
| 分子量 | Theoretical: 25 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |