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Anti-Phospho-Caldesmon (Ser789) Polyclonal Antibody 2
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还可以产品编号 TMAB-10436
Anti-Phospho-Caldesmon (Ser789) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Caldesmon (Ser789)。Anti-Phospho-Caldesmon (Ser789) Polyclonal Antibody 2 可用于 WB。
Anti-Phospho-Caldesmon (Ser789) Polyclonal Antibody 2
Anti-Phospho-Caldesmon (Ser789) Polyclonal Antibody 2
一键复制产品信息 还可以产品编号 TMAB-10436
Anti-Phospho-Caldesmon (Ser789) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Caldesmon (Ser789)。Anti-Phospho-Caldesmon (Ser789) Polyclonal Antibody 2 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
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| 产品描述 | Anti-Phospho-Caldesmon (Ser789) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Caldesmon (Ser789). Anti-Phospho-Caldesmon (Ser789) Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm, cytoskeleton. Cytoplasm, myofibril. Note=On thin filaments in smooth muscle and on stress fibers in fibroblasts (nonmuscle). |
| 组织特异性 | High-molecular-weight caldesmon (isoform 1) is predominantly expressed in smooth muscles, whereas low-molecular-weight caldesmon (isoforms 2, 3, 4 and 5) are widely distributed in non-muscle tissues and cells. Not expressed in skeletal muscle or heart. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jul 2008]. |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human Caldesmon around the phosphorylation site of Ser789 |
| 抗原种属 | Human |
| 基因名称 | CALD1 |
| 基因ID | |
| 蛋白名称 | Caldesmon |
| Uniprot ID | |
| 功能 | Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration. |
| 分子量 | Theoretical: 93 kDa. |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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