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5-Nitro-1,10-phenanthroline

Name: 5-Nitro-1,10-phenanthroline
Brand: TargetMol
SKU: T7735
Price: 112 CNY
Availability: InStock
Rating: 5 (10 reviews)

Synonyms: 5-硝基-1,10-菲咯啉, 5-NP

货号 T7735Cas号 4199-88-6 一键复制产品信息纯度: 99.5%

很棒

5-Nitro-1,10-phenanthroline (5-NP) 是一种有效的杀菌剂，可抑制艰难梭菌。

5-Nitro-1,10-phenanthroline

一键复制产品信息

很棒

纯度: 99.5%

货号 T7735Cas号 4199-88-6

别名 5-硝基-1,10-菲咯啉, 5-NP

5-Nitro-1,10-phenanthroline (5-NP) 是一种有效的杀菌剂，可抑制艰难梭菌。

规格	价格	库存
50 mg	¥ 148	现货
100 mg	¥ 198	现货
500 mg	¥ 768	现货
1 g	¥ 1,230	现货
1 mL x 10 mM (in DMSO)	¥ 112	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.5%

颜色: 黄色

性状: Solid

资源下载: COA LCMS HNMR HPLC产品操作手册

产品介绍

5-Nitro-1,10-phenanthroline AI Summary

5-Nitro-1,10-phenanthroline demonstrates an ability to associate with ferriprotoporphyrin IX, with a Log K value of 2.88. It exhibits mutagenic activity in an Ames test on Salmonella Typhimurium TA98, with an activity level of 0.59 log of revertants/nmol, and has a partition coefficient (logP) value of 1.84. Bioactivity assays show that 5-Nitro-1,10-phenanthroline potently inhibits Tau fibril formation, ALDH1A1, Mycobacterium tuberculosis H37Rv, Fructose-1,6-bisphosphate Aldolase, L3MBTL1, JMJD2A-Tudor Domain, BAZ2B, ELG1-dependent DNA repair, the malarial parasite plastid, Giardia lamblia, TGF-b, Vif-A3F interactions, GLP-1 receptor inverse agonists, Hepatitis C Virus (HCV), induces DNA re-replication, ATXN expression, human tyrosyl-DNA phosphodiesterase 1 (TDP1), and shows synthetic lethality in tumor cells producing 2HG, with potencies primarily in the nanomolar range. Additionally, 5-Nitro-1,10-phenanthroline exhibits antibacterial activity against Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus MRSA, and Acinetobacter baumannii, with inhibition ranging from 9.1% to 15.65%, and antifungal activity against Candida albicans, albeit lower at 0.77%. It demonstrates no efficacy against Cryptococcus neoformans. Against Mycobacterium tuberculosis H37Rv, it has a MIC99 of 0.78 µM, and it exhibits cytotoxicity against human THP-1 cells with a CC50 greater than 25,000 nM after 96 hours of treatment..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	5-Nitro-1,10-phenanthroline (5-NP)(5-NP) is a potent bactericidal agent and inhibiting Clostridium difficile.
别名	5-硝基-1,10-菲咯啉, 5-NP

化学信息

分子量	225.2
分子式	C₁₂H₇N₃O₂
CAS No.	4199-88-6
Smiles	[O-][N+](=O)C1=CC2=C(N=CC=C2)C2=C1C=CC=N2
密度	1.2844 g/cm3 (Estimated)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 11 mg/mL (48.85 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4405 mL	22.2025 mL	44.4050 mL	222.0249 mL
5 mM	0.8881 mL	4.4405 mL	8.8810 mL	44.4050 mL
10 mM	0.4440 mL	2.2202 mL	4.4405 mL	22.2025 mL
20 mM	0.2220 mL	1.1101 mL	2.2202 mL	11.1012 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。