- 全部删除
- 您的购物车当前为空
Anti-MST3 Antibody (8S853) 是一种 Mouse 抗体,靶向 MST3。Anti-MST3 Antibody (8S853) 可用于 WB,IP,IF。
Anti-MST3 Antibody (8S853) 是一种 Mouse 抗体,靶向 MST3。Anti-MST3 Antibody (8S853) 可用于 WB,IP,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,985 | 5日内发货 | |
100 μL | ¥ 2,985 | 5日内发货 |
产品描述 | Anti-MST3 Antibody (8S853) is a Mouse antibody targeting MST3. Anti-MST3 Antibody (8S853) can be used in WB,IP,IF. |
别名 | STK3, STE20, serine/threonine kinase 24, RP11-111L24.5, MST3B, MST3, HEL-S-95 |
克隆号 | 8S853 |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of MST-3 expression in non-transfected 293T (A), human MST-3 transfected 293T (B) and A-431 (C) whole cell lysates. 2. Immunofluorescence staining of HeLa cells showing cytoplasmic staining. |
应用 | |
推荐剂量 | WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Sterile-20 (STE20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to STE20 are divided into two groups, the PAK subfamily and the GCK subfamily. The PAK subfamily members contain a C-terminal catalytic domain and an N-terminal regulatory domain with a p21Rac/Cdc42-binding site, and these kinases can activate both p38 MAPK and JNK. The GCK subfamily members contain a C-terminal regulatory domain and an N-terminal catalytic domain, and they have diverse roles in many pathways, including the activation of ERK, JNK, p38 MAPK, and caspase-3. The mammalian STE20-like kinases (MST kinases, also known as Ksr proteins) are members of the GCK subfamily. Ksr-1 and Ksr-2 (also known as MST-2 and MST-1, respectively) are both direct substrates of caspase-3 that accelerate caspase-3 activation. MST-3 is ubiquitously expressed in mammalian tissue and can phosphorylate exogenous substrates as well as itself. MST-4 is highly expressed in placenta, thymus, and peripheral blood leukocytes, and it specifically activates ERK. |
偶联 | Unconjugated |
免疫原 | Amino acids 275-393 of MST-3 of human origin |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 50/35 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
评论内容