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Anti-MST3 Antibody (8S853)

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Anti-MST3 Antibody (8S853)
产品编号 TMAC-02664
别名 STK3, STE20, serine/threonine kinase 24, RP11-111L24.5, MST3B, MST3, HEL-S-95

Anti-MST3 Antibody (8S853) 是一种 Mouse 抗体,靶向 MST3。Anti-MST3 Antibody (8S853) 可用于 WB,IP,IF。

Anti-MST3 Antibody (8S853)

Anti-MST3 Antibody (8S853)

Rating icon 还可以
Anti-MST3 Antibody (8S853)
产品编号 TMAC-02664 别名 STK3, STE20, serine/threonine kinase 24, RP11-111L24.5, MST3B, MST3, HEL-S-95

Anti-MST3 Antibody (8S853) 是一种 Mouse 抗体,靶向 MST3。Anti-MST3 Antibody (8S853) 可用于 WB,IP,IF。

规格价格库存数量
50 μL
¥ 1,985
5日内发货
100 μL
¥ 2,985
5日内发货
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产品介绍

生物活性
产品描述
Anti-MST3 Antibody (8S853) is a Mouse antibody targeting MST3. Anti-MST3 Antibody (8S853) can be used in WB,IP,IF.
别名STK3, STE20, serine/threonine kinase 24, RP11-111L24.5, MST3B, MST3, HEL-S-95
克隆号
8S853
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of MST-3 expression in non-transfected 293T (A), human MST-3 transfected 293T (B) and A-431 (C) whole cell lysates.
2. Immunofluorescence staining of HeLa cells showing cytoplasmic staining.
应用
推荐剂量
WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Sterile-20 (STE20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to STE20 are divided into two groups, the PAK subfamily and the GCK subfamily. The PAK subfamily members contain a C-terminal catalytic domain and an N-terminal regulatory domain with a p21Rac/Cdc42-binding site, and these kinases can activate both p38 MAPK and JNK. The GCK subfamily members contain a C-terminal regulatory domain and an N-terminal catalytic domain, and they have diverse roles in many pathways, including the activation of ERK, JNK, p38 MAPK, and caspase-3. The mammalian STE20-like kinases (MST kinases, also known as Ksr proteins) are members of the GCK subfamily. Ksr-1 and Ksr-2 (also known as MST-2 and MST-1, respectively) are both direct substrates of caspase-3 that accelerate caspase-3 activation. MST-3 is ubiquitously expressed in mammalian tissue and can phosphorylate exogenous substrates as well as itself. MST-4 is highly expressed in placenta, thymus, and peripheral blood leukocytes, and it specifically activates ERK.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Amino acids 275-393 of MST-3 of human origin
抗原种属
human
Uniprot ID
化学信息
分子量Theoretical: 50/35 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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