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Anti-Contactin 3 Antibody (8J989)
还可以产品编号 TMAY-00403
Anti-Contactin 3 Antibody (8J989) 是一种 Mouse 抗体，靶向 Contactin 3。Anti-Contactin 3 Antibody (8J989) 可用于 ELISA。
Anti-Contactin 3 Antibody (8J989)
Anti-Contactin 3 Antibody (8J989)
还可以产品编号 TMAY-00403
Anti-Contactin 3 Antibody (8J989) 是一种 Mouse 抗体，靶向 Contactin 3。Anti-Contactin 3 Antibody (8J989) 可用于 ELISA。
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抗原信息
| 产品描述 | Anti-Contactin 3 Antibody (8J989) is a Mouse antibody targeting Contactin 3. Anti-Contactin 3 Antibody (8J989) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 8J989 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Contactin-3 (rh CNTN3; TMPY-00723; Met1-Ser1002,708Asp/Asn; NP_065923.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography . |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2 (TAG-1), Contactin-3 (BIG-1), BIG-2, Contactin-5 (NB-2) and NB-3. Since their identification in the late 1980s, Contactin-1 and Contactin-2 have been studied extensively. Axonal expression and the neurite extension activity of Contactin-1 and Contactin-2 attracted researchers to study the function of these molecules in axon guidance during development. Contactin-1 and Contactin-2 have come to be known as the principal molecules in the function and maintenance of myelinated neurons. In contrast, the function of the other four members of this subgroup remained unknown until recently. Contactin-3, also known as CNTN3 (BIG-1 in rat and PANG in mouse), is a GPI-linked glycoprotein that is expressed on cerebellar Purkinje cells, amygdaloid and thalamic neurons and olfactory granule cells. In the brain, Contactin-3 is expressed in frontal lobe, occipital lobe, cerebellum and amygdala. Contactin-3 contains 4 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. Human Contactin-3 shares 92% aa identity with mouse Contactin-3. The exact function of Contactin-3 is unclear. Contactin-3 may mediate cell-cell interaction and may promote neurite outgrowth. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CNTN3 protein (TMPY-00723) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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