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Anti-IFNAR1 Antibody (6J318)

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产品编号 TMAC-02086

别名 干扰素

Anti-IFNAR1 Antibody (6J318) 是一种 Mouse 抗体，靶向 IFNAR1。Anti-IFNAR1 Antibody (6J318) 可用于 FCM,IP,WB。

Anti-IFNAR1 Antibody (6J318)

Anti-IFNAR1 Antibody (6J318)

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Rating icon 还可以
产品编号 TMAC-02086 别名 干扰素

Anti-IFNAR1 Antibody (6J318) 是一种 Mouse 抗体，靶向 IFNAR1。Anti-IFNAR1 Antibody (6J318) 可用于 FCM,IP,WB。

规格价格库存数量
50 μL
¥ 1,990
5日内发货
100 μL
¥ 2,985
5日内发货
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产品介绍

生物活性
产品描述
Anti-IFNAR1 Antibody (6J318) is a Mouse antibody targeting IFNAR1. Anti-IFNAR1 Antibody (6J318) can be used in FCM,IP,WB.
别名干扰素
克隆号
6J318
交叉反应
Mouse
应用FCMIPWB
推荐剂量
WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate); FCM: 1 μg per 1 x 106 cells
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The type I interferons (IFNs), ? and ∫, are a group of structurally and functionally related proteins that are induced by either viruses or double stranded RNA and defined by their ability to confer an antiviral state in cells. The ? and ∫ IFNs appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN?) binds to a distinct receptor. The latter protein, IFN-?R, is only weakly responsive to type I interferons in contrast to IFN-?/∫R, which binds to and responds effectively to IFN-∫ and to several of the IFN-? subtypes. Moreover, IFN-?/∫R is physically associated with the cytoplasmic tyrosine kinase JAK1 and thus, in addition to ligand binding, appears to be functionally involved in signal transduction. IFN-?R1 is a receptor for IFN-?/∫ and is present as the full chain (IFN-?R1a) and as a splice-variant (IFN-?R1). The IFN-? receptor complex consists of an alpha subunit (IFN-?R?) and a beta subunit that is 332 amino acids in length (mouse) and 337 amino acids in length (human).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
The extracellular domain of IFN-αR1 of mouse origin
抗原种属
mouse
Uniprot ID
P33896
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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