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Anti-HOPX/LAGY Polyclonal Antibody

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货号 TMAB-07238

Anti-HOPX/LAGY Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HOPX/LAGY。Anti-HOPX/LAGY Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-HOPX/LAGY Polyclonal Antibody

Anti-HOPX/LAGY Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07238

Anti-HOPX/LAGY Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HOPX/LAGY。Anti-HOPX/LAGY Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-HOPX/LAGY Polyclonal Antibody is a Rabbit antibody targeting HOPX/LAGY. Anti-HOPX/LAGY Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Widely expressed. Expressed in the heart, brain, placenta, lung, skeletal and smooth muscles, uterus, urinary bladder, kidney and spleen. Down-regulated in some types of cancer such as lung cancer, choriocarcinoma, head and neck squamous cell carcinoma and oral squamous cell carcinoma.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Feb 2009]
抗原信息
免疫原
KLH conjugated synthetic peptide: human HOPX/LAGY
抗原种属
Human
基因名称
HOPX
基因ID
蛋白名称
Homeodomain-only protein
Uniprot ID
功能
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.
化学信息
分子量Theoretical: 8 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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