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Anti-Human IgM Antibody (7U224) 是一种 Rabbit 抗体,靶向 Human IgM。Anti-Human IgM Antibody (7U224) 可用于 WB,IHC,IP。
Anti-Human IgM Antibody (7U224) 是一种 Rabbit 抗体,靶向 Human IgM。Anti-Human IgM Antibody (7U224) 可用于 WB,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-Human IgM Antibody (7U224) is a Rabbit antibody targeting Human IgM. Anti-Human IgM Antibody (7U224) can be used in WB,IHC,IP. |
别名 | VH, MU, MGC52291, MGC104996, Immunoglobulin mu, Immunoglobin heavy constant mu, Immunoglobin heavy chain constant region mu edit item name - Immunoglobin heavy chain mu constant region, Immunoglobin heavy chain constant region mu, IgM heavy chain constant region, IGHM, Ig mu chain C region, FLJ00385, DKFZp686I15212, DKFZp686I15196, Constant region of heavy chain of IgM, AGM1 |
Ig Type | IgG |
克隆号 | 7U224 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of Human IgM on human plasma lysates using anti-Human IgM antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Human IgM antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Human IgM antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000-5000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Immunoglobulin M (IgM) is the largest circulating antibody molecule in humans. It consists of a heavy chain (?-chain) and a light chain (κ- or λ-chain), as well as 5 base units and 10 binding sites, though it cannot bind all 10 simultaneously because of steric hindrance. IgM chain C refers to the constant region of the IgM heavy chain that is involved in immune regulation. IgM forms polymers by covalently linking multiple immunoglobulins together with disulfide bonds. It normally exists as a pentamer, but occasionally as a hexamer. Because of its polymeric nature, IgM has high avidity, and it is especially effective at complement activation. Due to its large size, IgM does not diffuse well, and it is found in the interstitium in very low amounts. IgM is mainly found in serum; however, because of the J chain, it is also important as a secretory immunoglobulin. IgM is the first immunoglobulin expressed by mature B cells, and it normally appears early in the course of an infection and does not reappear after further exposure. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 75 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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