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Anti-ITPR3 Polyclonal Antibody

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货号 TMAB-07847

Anti-ITPR3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ITPR3。Anti-ITPR3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-ITPR3 Polyclonal Antibody

Anti-ITPR3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07847

Anti-ITPR3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ITPR3。Anti-ITPR3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-ITPR3 Polyclonal Antibody is a Rabbit antibody targeting ITPR3. Anti-ITPR3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:50-200
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane.
组织特异性Expressed in intestinal crypt and villus epithelial cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ITPR3
抗原种属
Human
基因名称
ITPR3
基因ID
蛋白名称
Inositol 1, 4, 5-trisphosphate receptor type 3
Uniprot ID
功能
Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells.
化学信息
分子量Theoretical: 294 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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