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顶部生物活性储存和溶解信息计算器

Anti-CDC7 Kinase Antibody (5I139)

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Anti-CDC7 Kinase Antibody (5I139)
产品编号 TMAC-00774
别名 MGC126238, MGC126237, MGC117361, huCdc7, HuCDC 7, Hsk1, Hsk 1, HsCdc7, HsCDC 7, Cell division cycle 7-related protein kinase, Cell division cycle 7 related protein kinase, Cell division cycle 7 like protein 1, Cell division cycle 7 kinase, Cell division cycle 7 homolog, CDC7-related kinase, CDC7L1, CDC7L 1, CDC7_HUMAN, CDC7 related kinase, Cdc7 like 1, CDC7 L1, CDC7 cell division cycle 7 like 1, CDC7 cell division cycle 7, Cdc 7

Anti-CDC7 Kinase Antibody (5I139) 是一种 Rabbit 抗体，靶向 CDC7 Kinase。Anti-CDC7 Kinase Antibody (5I139) 可用于 WB,FCM。

Anti-CDC7 Kinase Antibody (5I139)

Anti-CDC7 Kinase Antibody (5I139)

Rating icon 还可以
Anti-CDC7 Kinase Antibody (5I139)
产品编号 TMAC-00774 别名 MGC126238, MGC126237, MGC117361, huCdc7, HuCDC 7, Hsk1, Hsk 1, HsCdc7, HsCDC 7, Cell division cycle 7-related protein kinase, Cell division cycle 7 related protein kinase, Cell division cycle 7 like protein 1, Cell division cycle 7 kinase, Cell division cycle 7 homolog, CDC7-related kinase, CDC7L1, CDC7L 1, CDC7_HUMAN, CDC7 related kinase, Cdc7 like 1, CDC7 L1, CDC7 cell division cycle 7 like 1, CDC7 cell division cycle 7, Cdc 7

Anti-CDC7 Kinase Antibody (5I139) 是一种 Rabbit 抗体，靶向 CDC7 Kinase。Anti-CDC7 Kinase Antibody (5I139) 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-CDC7 Kinase Antibody (5I139) is a Rabbit antibody targeting CDC7 Kinase. Anti-CDC7 Kinase Antibody (5I139) can be used in WB,FCM.
别名MGC126238, MGC126237, MGC117361, huCdc7, HuCDC 7, Hsk1, Hsk 1, HsCdc7, HsCDC 7, Cell division cycle 7-related protein kinase, Cell division cycle 7 related protein kinase, Cell division cycle 7 like protein 1, Cell division cycle 7 kinase, Cell division cycle 7 homolog, CDC7-related kinase, CDC7L1, CDC7L 1, CDC7_HUMAN, CDC7 related kinase, Cdc7 like 1, CDC7 L1, CDC7 cell division cycle 7 like 1, CDC7 cell division cycle 7, Cdc 7
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of CDC7 Kinase on different lysates using anti-CDC7 antibody at 1/1,000 dilution. Positive control: Lane 1: Jurkat, Lane 2: Hela.
2. Flow cytometric analysis of A431 cells with CDC7 Kinase antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
WB
FCM
推荐剂量
WB: 1:1000-5000; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The Dbf4/Cdc7 protein kinase is essential for the activation of replication origins during S phase. Cdc7/Dbf4 efficiently phosphorylates several proteins that are required for the initiation of DNA replication, including five of the six minichromosome maintenance (Mcm) proteins and the p180 subunit of DNA polymerase a-primase. This protein complex consists of the catalytic subunit Cdc7 associating with the regulatory and activating subunit Dbf4. The kinase activity of the complex is regulated throughout the cell cycle, mainly by fluctuating levels of Dbf4. Cdc7 is consistently expressed throughout the cell cycle, while the expression of Dbf4 is absent during G1 phase and accumulates during S and G2 phases. The anaphase-promoting complex rapidly degrades Dbf4 at the time of chromosome segregation, and the stability of Dbf4 remains low during pre-Start G1 phase. The coordinated degradation of Dbf4 and the time of chromosome separation is important to ensuring that prereplicative complexes, which assemble after chromosome segregation, do not immediately refire.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
O00311
化学信息
分子量Theoretical: 64 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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