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Anti-human CD35 Antibody (5H190)

货号 TMAB-07405 一键复制产品信息
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Anti-human CD35 Antibody (5H190) 是一种 Mouse 抗体,靶向 human CD35。Anti-human CD35 Antibody (5H190) 可用于 FCM。

Anti-human CD35 Antibody (5H190)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07405

Anti-human CD35 Antibody (5H190) 是一种 Mouse 抗体,靶向 human CD35。Anti-human CD35 Antibody (5H190) 可用于 FCM。

Anti-human CD35 Antibody (5H190)
规格价格库存数量
100 μg
¥ 1,860
5日内发货
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产品介绍


生物活性
产品描述
Anti-human CD35 Antibody (5H190) is a Mouse antibody targeting human CD35. Anti-human CD35 Antibody (5H190) can be used in FCM.
Ig Type
Mouse IgG1, k
克隆号
5H190
反应种属
Human
验证活性
Blank control: HEL.
Primary Antibody (green line): Mouse Anti-human CD35 antibody (TMAB-07405)
Dilution: 2 μg/Test;
Secondary Antibody (white blue line) : Goat anti-mouse IgG-FITC
Dilution: 0.5 μg/Test.
Isotype control (orange line): Normal Mouse IgG
Protocol
The cells were incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
应用FCM
推荐剂量
FCM: 2μg/Test
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Present on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4).
研究背景This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The genome is polymorphic at this locus with allele-specific splice variants encoding different isoforms, based on the presence/absence of long homologous repeats (LHRs). The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in this gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus, sarcoidosis and Alzheimer's disease. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. [provided by RefSeq, May 2020]
抗原信息
基因名称
CR1
基因ID
蛋白名称
Complement receptor type 1
功能
Mediates cellular binding of particles and immune complexes that have activated complement.
化学信息
分子量Theoretical: 274 kDa. Actual: 160, 190, 220, and 250 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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