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Anti-human CD35 Antibody (5H190) 是一种 Mouse 抗体,靶向 human CD35。Anti-human CD35 Antibody (5H190) 可用于 FCM。
Anti-human CD35 Antibody (5H190) 是一种 Mouse 抗体,靶向 human CD35。Anti-human CD35 Antibody (5H190) 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μg | ¥ 1,860 | 5日内发货 |
| 产品描述 | Anti-human CD35 Antibody (5H190) is a Mouse antibody targeting human CD35. Anti-human CD35 Antibody (5H190) can be used in FCM. |
| Ig Type | Mouse IgG1, k |
| 克隆号 | 5H190 |
| 反应种属 | Human |
| 验证活性 | Blank control: HEL. Primary Antibody (green line): Mouse Anti-human CD35 antibody (TMAB-07405) Dilution: 2 μg/Test; Secondary Antibody (white blue line) : Goat anti-mouse IgG-FITC Dilution: 0.5 μg/Test. Isotype control (orange line): Normal Mouse IgG Protocol The cells were incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed. |
| 应用 | FCM |
| 推荐剂量 | FCM: 2μg/Test |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Present on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4). |
| 研究背景 | This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The genome is polymorphic at this locus with allele-specific splice variants encoding different isoforms, based on the presence/absence of long homologous repeats (LHRs). The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in this gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus, sarcoidosis and Alzheimer's disease. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. [provided by RefSeq, May 2020] |
| 基因名称 | CR1 |
| 基因ID | |
| 蛋白名称 | Complement receptor type 1 |
| 功能 | Mediates cellular binding of particles and immune complexes that have activated complement. |
| 分子量 | Theoretical: 274 kDa. Actual: 160, 190, 220, and 250 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |