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顶部生物活性储存和溶解信息计算器

Anti-IKZF1 Antibody (2W313)

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产品编号 TMAH-00605

Anti-IKZF1 Antibody (2W313) 是一种抗体，靶向 IKZF1。Anti-IKZF1 Antibody (2W313) 可用于 ELISA,FCM。

Anti-IKZF1 Antibody (2W313)

Anti-IKZF1 Antibody (2W313)

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Rating icon 还可以
产品编号 TMAH-00605

Anti-IKZF1 Antibody (2W313) 是一种抗体，靶向 IKZF1。Anti-IKZF1 Antibody (2W313) 可用于 ELISA,FCM。

规格价格库存数量
50 μL
¥ 1,315
5日内发货
100 μL
¥ 2,180
5日内发货
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产品介绍

生物活性
产品描述
Anti-IKZF1 Antibody (2W313) is an antibody targeting IKZF1. Anti-IKZF1 Antibody (2W313) can be used in ELISA,FCM.
Ig Type
Rabbit IgG
克隆号
2W313
交叉反应
Human
验证活性
Overlay Peak curve showing Jurkat cells stained with TMAH-00605 (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed.
应用ELISAFCM
推荐剂量
FCM:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Nucleus.; [Isoform Ik2]: Nucleus.; [Isoform Ik6]: Cytoplasm.
组织特异性Abundantly expressed in thymus, spleen and peripheral blood Leukocytes and lymph nodes. Lower expression in bone marrow and small intestine.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs). Function is isoform-specific and is modulated by dominant-negative inactive isoforms.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human IKZF1
抗原种属
Human
基因名称
IKZF1
基因ID
10320
Uniprot ID
Q13422
研究领域
Epigenetics and Nuclear Signaling, Cancer
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

ZNFN1A1ZNFN1A 1Lymphoid transcription factor LyF-1LYF1LYF 1IKZF1IKZF 1Ikaros family zinc finger protein 1IKAROSIK1IK 1DNA-binding protein Ikaros

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