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Anti-CXCR3 Antibody (8K493) 是一种 Rabbit 抗体,靶向 CXCR3。Anti-CXCR3 Antibody (8K493) 可用于 WB,ICC/IF,IP。
Anti-CXCR3 Antibody (8K493) 是一种 Rabbit 抗体,靶向 CXCR3。Anti-CXCR3 Antibody (8K493) 可用于 WB,ICC/IF,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-CXCR3 Antibody (8K493) is a Rabbit antibody targeting CXCR3. Anti-CXCR3 Antibody (8K493) can be used in WB,ICC/IF,IP. |
别名 | Mig-R, MigR, IP10-R, GPR9, CMKAR3, CKR-L2, CD183, CD182 |
Ig Type | IgG |
克隆号 | 8K493 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of CXCR3 on Hela cell using anti-CXCR3 antibody at 1/1,000 dilution. 2. ICC staining CXCR3 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining CXCR3 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining CXCR3 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
应用 | |
推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The C-X-C or α chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). SDF-1 was originally described as a pre-B cell stimulatory factor, but has since been shown to function as a potent chemoattractant for T cells and monocytes but not neutrophils. Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins which include IL-8RA, IL-8RB, CXCR-3 and fusin (also designated LESTR or CXCR-4). CXCR-3, also known as IP-10/MIG receptor, mediates Ca2+ mobilization and chemotaxis in response to the C-X-C chemokines IP-10 and MIG. CXCR-3 is highly expressed in IL-2-activated T lymphocytes, but not in resting T lymphocytes, B lymphocytes, monocytes or granulocytes. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 41 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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