规格

价格

库存

数量

1 mg

¥ 1,650

现货

生物活性

产品描述	G907 is a selective and potent antagonist of the small molecule ATP-binding cassette (ABC) transporter protein MsbA, with bactericidal activity, which traps MsbA in the inner lipopolysaccharide. G907 inhibits E. coli MsbA with an IC50 value of 18 nM.
靶点活性	MsbA:18 nM
体外活性	G907 inhibits the activity of purified Escherichia coli MsbA with an IC50 value of 18 nM over a concentration range of 0.1 nM to 100 μM[1]. G907 exhibits allosteric inhibitory activity against MsbA[2]. At 100 nM, G907 completely inhibits the transport activity of biotin-PE in liposomes containing MsbA-WT protein[1].

化学信息

分子量	433.93
分子式	C₂₆H₂₄ClNO₃
CAS No.	2244035-16-1
Smiles	CC(Oc1ccc2ncc(\C=C\C(O)=O)c(C3CC3)c2c1)c1c(Cl)cccc1C1CC1
密度	1.346 g/cm3 (Predicted)
颜色	White
物理性状	Solid

储存&溶解度

存储

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 60 mg/mL (138.27 mM), Sonication is recommended.

体内实验配方

10% DMSO+90% Corn Oil: 2.5 mg/mL (5.76 mM), Sonication is recommeded.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

G907