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Anti-SNX6 Polyclonal Antibody

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货号 TMAB-13013

Anti-SNX6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SNX6。Anti-SNX6 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-SNX6 Polyclonal Antibody

Anti-SNX6 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13013

Anti-SNX6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SNX6。Anti-SNX6 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-SNX6 Polyclonal Antibody is a Rabbit antibody targeting SNX6. Anti-SNX6 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Pig,Cow,Horse,Rabbit,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Nucleus. Note=Interaction with SNX1 or SNX2 promotes location at endosome membranes. Only a minor proportion is seen in the nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Two related proteins, TRAF1 and TRAF2 (TNF receptor-associated factors 1 and 2, respectively), form a heterodimeric complex that associates with the cytoplasmic domain of the tumor necrosis factor (TNF) receptor type 2 (1). A third member of this family, TRAF3 (also designated CD40bp or CRAF1) associates with the cytoplasmic domain of CD40 (2). Additional membersof the TRAF/CRAF family of signaling intermediates include TRAF4 (also designated CART1), TRAF5 and TRAF6 (3-5). TRAF4 associated factor 2 (TRAF4-AF2), also designated sorting nexin 6 (SNX6), is a member of the sorting nexin family of molecules, which are widely expressed and associate with various receptor (6).
抗原信息
免疫原
KLH conjugated synthetic peptide: human SNX6
抗原种属
Human
基因名称
SNX6
基因ID
58533
蛋白名称
Sorting nexin-6
Uniprot ID
Q9BUY3
功能
Snx6 is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms.
化学信息
分子量Theoretical: 47 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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