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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-USP28 Polyclonal Antibody

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货号 TMAB-14021

Anti-USP28 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 USP28。Anti-USP28 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-USP28 Polyclonal Antibody

Anti-USP28 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-14021

Anti-USP28 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 USP28。Anti-USP28 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-USP28 Polyclonal Antibody is a Rabbit antibody targeting USP28. Anti-USP28 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability. Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN. Also involved in G2 DNA damage checkpoint, by deubiquitinating CLSPN, and preventing its degradation by the anaphase promoting complex/cyclosome (APC/C). In contrast, it does not deubiquitinate PLK1. Specifically deubiquitinates MYC in the nucleoplasm, leading to prevent MYC degradation by the proteasome: acts by specifically interacting with isoform 1 of FBXW7 (FBW7alpha) in the nucleoplasm and counteracting ubiquitination of MYC by the SCF(FBW7) complex. In contrast, it does not interact with isoform 4 of FBXW7 (FBW7gamma) in the nucleolus, allowing MYC degradation and explaining the selective MYC degradation in the nucleolus.
抗原信息
免疫原
KLH conjugated synthetic peptide: human USP28
抗原种属
Human
基因名称
USP28
基因ID
57646
蛋白名称
Ubiquitin carboxyl-terminal hydrolase 28
Uniprot ID
Q96RU2
化学信息
分子量Theoretical: 75/100 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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